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A new mechanism involving intermediate gating states of calcium channels explains how analogue postsynaptic potentials influence neurotransmitter release.

New evidence in mice suggests that cells expressing the transcription factor FOXC2 may form a reservoir of quiescent stem cells that contributes to sperm formation.

Accumulation of iron with age may inhibit the benefits of hormone replacement therapy on cardiovascular disease in late postmenopause.

A study of sea urchin and sea star larvae paves the way for understanding how cell types evolve and give rise to novel morphologies.

The simultaneous delivery of protein and lipid antigens via nanoparticles may help efforts to develop a new vaccine for tuberculosis.

Studying the nutrient composition immediately surrounding pancreatic cancer cells provides new insights into their metabolic properties and how they can evade the immune system to promote disease progression.

Newly developed tools will help researchers understand how the human heart develops and build better models to study and treat congenital heart disease.

Analysis of specimens preserved in amber from the Cretaceous period suggests that nematodes changed their host preference towards insects with a complete metamorphosis more recently.

Genomic analysis has shed light on how hadal snailfish have adapted to living at depths of several thousand metres.

Inhibitory circuit motifs in the mouse brain and the human brain are strikingly similar.