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The lymphatic and blood network of the mouse epididymis in adulthood and during postnatal ontogeny has been analyzed in detail.

In awake behaving rats, cholinergic interneurons in the nucleus accumbens drive dopamine release via nicotinic receptors, boosting motivation to work.

Experimentation on patient biopsies, cell culture, and xenograft models demonstrates involvement of ErbB signaling and fibroblasts in lesion growth, implying that targeting of both stromal and endothelial cells could be a beneficial treatment strategy for patients with venous lesions.

Deletion of Arginase 1 in myeloid cells delays tumor formation in pancreatic cancer.

A combination of in vivo and in vitro approaches using Xenopus eggs and embryos reveals how dimensions of mitotic chromosomes scale with decreasing cell size and increasing nuclear-cytoplasmic ratio during early embryogenesis.

Transcriptional activation of the orphan nuclear receptor Nurr1 by ligands targeting its heterodimer partner retinoid X receptor alpha (RXRα) occurs through a nonclassical pharmacological mechanism involving ligand-binding domain protein-protein interaction inhibition.

The prolactin receptor, Janus kinase 2, and PI(4,5)P₂ form a co-structure with the membrane resulting in orientations with different accessibility fixing the disordered juxtamembrane domain of the receptor in an extended structure.

Inter-individual variabilities in nicotine aversion are linked with responses of the interpeduncular nucleus to the drug.

Single-peaked tuning curves found in early sensory areas are more optimized for quick decoding than accuracy, while multi-peaked tuning curves (e.g. grid cells) give higher accuracy but only at longer time scales.

While tau and aging have highly overlapping differential gene expression signatures, they diverge in the affected cell types, with aging having a wide-ranging impact and tau-triggered changes instead polarized to excitatory neurons and glia.