Browse our Research Articles

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    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

    Aurore L'honoré, Pierre-Henri Commère ... Didier Montarras
    Modulation of muscle stem cell redox state in culture both improves their amplification while maintaining a similar grafting potential as freshly isolated stem cells.
    1. Cell Biology

    Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

    Kathryn E Kistler, Tatjana Trcek ... Ruth Lehmann
    The scaffolding protein Oskar organizes two types of germ granules by phase transition within the same cell but with distinct morphologies, composition and biological functions.
    1. Neuroscience

    Normal cognitive and social development require posterior cerebellar activity

    Aleksandra Badura, Jessica L Verpeut ... Samuel S-H Wang
    Social and cognitive functions require normal activity during development of the posterior cerebellum.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system

    Rupamanjari Majumder, Iolanda Feola ... Daniel A Pijnappels
    Free optical steering of spiral waves by attraction-based dragging of their cores in optogenetically modified cardiac tissue.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria

    Alam García-Heredia, Amol Arunrao Pohane ... M Sloan Siegrist
    Peptidoglycan precursor synthesis occurs in both growing and non-growing regions of the mycobacterial cell surface.
    1. Neuroscience

    Humidity response depends on the small soluble protein Obp59a in Drosophila

    Jennifer S Sun, Nikki K Larter ... John R Carlson
    Hygroreception, a poorly understood process critical to insect survival, depends on a small protein in the antenna of the fruit fly that was previously thought to transport odorants.
    1. Genetics and Genomics

    Firefly genomes illuminate parallel origins of bioluminescence in beetles

    Timothy R Fallon, Sarah E Lower ... Jing-Ke Weng
    The first genomic view of beetle luciferase evolution indicates evolutionary independence of luciferase between fireflies and click-beetles, and provide valuable datasets which will accelerate the discovery of new biotechnological tools.
    1. Evolutionary Biology

    A biological switching valve evolved in the female of a sex-role reversed cave insect to receive multiple seminal packages

    Kazunori Yoshizawa, Yoshitaka Kamimura ... Alexander Blanke
    The discovery of a biological switching valve provides an example of a mechanism that evolved in nature long before its invention by man and could inspire alternative valve technologies.
    1. Computational and Systems Biology
    2. Neuroscience

    Learning recurrent dynamics in spiking networks

    Christopher M Kim, Carson C Chow
    Modifying the recurrent connectivity of spiking networks provides sufficient flexibility to generate arbitrarily complex recurrent dynamics, suggesting that individual neurons in a recurrent network have the capability to support near universal dynamics.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Rif1 inhibits replication fork progression and controls DNA copy number in Drosophila

    Alexander Munden, Zhan Rong ... Jared T Nordman
    To regulate DNA copy number during development in Drosophila, the SUUR protein recruits Rif1 to replisomes where Rif1 inhibits replication fork progression, thus controlling copy number independently of origin firing.