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UPF1 mutations were reportedly present at high frequencies in a cohort of pancreatic adenosquamous carcinoma patients, but these lesions are unlikely to be functional drivers of this cancer subtype.

Acquisition of antibiotic resistance plasmids induces collateral sensitivity to clinically relevant antibiotics in Escherichia coli, paving the way for targeted 'anti-plasmid' therapies able to preferentially eliminate plasmid-carrying bacteria.

The loss of Mecp2 results in cerebellar dysfunction that contributes to the motor deficits in Rett syndrome.

Longitudinal tracking of individual T-cell clones reveals the expansion of pre-existing T-cell memory in response to SARS-CoV-2 infection.

Post-acute or long-COVID is associated with bystander T-cell activation and a recurring antimicrobial resistant, bacterial ventilator-associated pneumonia.

Comparative genomics and three-dimensional protein modelling identify homologs of insect chemosensory receptors in unicellular eukaryotes and plants.

Light controls can fine tune microbiome–host interaction to qualitatively regulate host longevity with temporal and spatial precision.

A larger non-recombining region in sexually dimorphic primates compared to sexually monomorphic ones supports the view that sexually antagonistic mutations have influenced the evolution of sex chromosomes in primates.

Crosslinking the AAA+ protease interface does not abolish protein degradation by ClpAP, establishing that rotation of the AAA+ unfoldase with respect to its partner peptidase is not essential for activity.

The neuronal activity in primary motor cortex does not exhibit smooth low-dimensional dynamics during grasp as it does during reach.