Browse our Short Reports

Page 21 of 62
    1. Evolutionary Biology

    Preliminary paleohistological observations of the StW 573 (‘Little Foot’) skull

    Amélie Beaudet, Robert C Atwood ... Dominic Stratford
    Virtual investigation of the 3.67-million-year-old skull of 'Little Foot' using synchrotron radiation reveals histological details of Australopithecus dental and bone tissues.
    1. Neuroscience

    Control of feeding by Piezo-mediated gut mechanosensation in Drosophila

    Soohong Min, Yangkyun Oh ... Stephen Liberles
    Gut-innervating sensory neurons detect large food volumes and inhibit feeding in Drosophila through the mechanically gated ion channel Piezo.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation

    Pengfei Xu, Haoze V Yu ... J Gage Crump
    Foxc1 proteins prepare the genomes of neural crest-derived cells to facilitate their later development into the cartilages that support the embryonic face.
    1. Epidemiology and Global Health

    Protective effect of Mediterranean-type glucose-6-phosphate dehydrogenase deficiency against Plasmodium vivax malaria

    Ghulam R Awab, Fahima Aaram ... Nicholas J White
    The Mediterranean variant of glucose-6-phosphate dehydrogenase deficiency confers a strong gene-dose proportional protective effect against symptomatic Plasmodium vivax malaria in the Pashtun ethnic group.
    1. Neuroscience

    Leptin receptor neurons in the dorsomedial hypothalamus regulate diurnal patterns of feeding, locomotion, and metabolism

    Chelsea L Faber, Jennifer D Deem ... Gregory J Morton
    Synchronized feeding and metabolic patterns with environmental light–dark cycles is critical to maintain energy homeostasis and requires the activity of leptin-receptor neurons in the dorsomedial hypothalamus.
    1. Immunology and Inflammation
    2. Medicine

    Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2

    Kelsey E Huntington, Anna D Louie ... Wafik S El-Deiry
    A mutual information algorithm points to macrophage activation syndrome as a specific pathogenic mechanism in COVID-19, correlated with disease severity, which could be used to monitor disease and therapeutics.
    1. Biochemistry and Chemical Biology

    Membrane-partitioned cell wall synthesis in mycobacteria

    Alam García-Heredia, Takehiro Kado ... M Sloan Siegrist
    Mycobacteria employ plasma membrane compartments to organize their cell wall synthesis, and the finalized cell wall compartmentalizes the plasma membrane to promote an environment conducive to its own synthesis.
    1. Neuroscience

    fruitless tunes functional flexibility of courtship circuitry during development

    Jie Chen, Sihui Jin ... Yufeng Pan
    The courtship master gene fruitless tunes functional flexibility of courtship circuitry during development instead of switching on its function as conventionally viewed.
    1. Neuroscience

    Spatial modulation of visual responses arises in cortex with active navigation

    E Mika Diamanti, Charu Bai Reddy ... Matteo Carandini
    Spatial modulation along the visual pathway arises in the cortex and strengthens with active navigation and experience.
    1. Cell Biology

    A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

    Xue Chen, Haidong Yao ... Martin O Bergo
    Knockout of the methyltransferase ICMT prevents progerin methylation and improves survival in mice with Hutchinson-Gilford progeria syndrome (HGPS) and an ICMT inhibitor delays senescence and stimulates proliferation of HGPS cells.