Cell Biology

Latest articles

1. 1. Cell Biology
   2. Cancer Biology

   Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

   Camille Dantzer, Justine Vaché ... Violaine Moreau
2. 1. Cell Biology
   2. Physics of Living Systems

   Partitioning to ordered membrane domains regulates the kinetics of secretory traffic

   Ivan Castello-Serrano, Frederick A Heberle ... Ilya Levental

   Direct measurements of trafficking kinetics between organelles of the secretory pathway suggest that lipid-driven membrane domains laterally sort proteins during membrane traffic.
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Live imaging of Alu elements reveals non-uniform euchromatin dynamics coupled to transcription

   Yi-Che Chang, Sofia A. Quinodoz, Clifford P. Brangwynne
4. 1. Cell Biology
   2. Microbiology and Infectious Disease

   High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection

   Ana T. López-Jiménez, Dominik Brokatzky ... Serge Mostowy
5. 1. Cell Biology

   Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

   Saori Shinoda, Yuji Sakai ... Noboru Mizushima

   The autophagosomal membrane becomes negatively charged during maturation due to the accumulation of PI4P, leading to the recruitment of syntaxin 17, which is required for autophagosome-lysosome fusion.
6. 1. Cell Biology

   Membrane Fusion: A matter of timing

   Zhiqi Tian, Jiajie Diao

   A change in the electric charge of autophagosome membranes controls the recruitment of SNARE proteins to ensure that membrane fusion occurs at the right time during autophagy.
7. 1. Cell Biology

   Quantitative intra-Golgi transport and organization data suggest the stable compartment nature of the Golgi

   Hieng Chiong Tie, Haiyun Wang ... Lei Lu
8. 1. Cell Biology
   2. Developmental Biology

   SRSF2 is a key player in orchestrating the directional migration and differentiation of MyoD progenitors during skeletal muscle development

   Rula Sha, Ruochen Guo ... Ying Feng
9. 1. Cell Biology
   2. Computational and Systems Biology

   Agent-based model demonstrates the impact of nonlinear, complex interactions between cytokines on muscle regeneration

   Megan Haase, Tien Comlekoglu ... Silvia S Blemker

   A computational model of skeletal muscle regeneration reveals complex interplay of cytokines, angiogenesis, and cell behaviors, predicting that synergistic cytokine perturbations enhance skeletal muscle regeneration beyond individual cytokine interventions.
10. 1. Cell Biology
    2. Genetics and Genomics

    Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling

    Jiali Chen, Qinghe Zeng ... Hongting Jin

    Alterations of DNA methylation were associated with articular cartilage degeneration in hemophilic arthropathy, and aberrant methylation and expression of TNXB promote blood-induced chondrocyte apoptosis by regulating AKT activation.