Cell Biology

Latest articles

1. 1. Cancer Biology
   2. Cell Biology

   N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotion

   Julian JA Hoving, Elizabeth Harford-Wright ... Alison C Lloyd

   N-cadherin and Slit2/3/Robo interactions provide the outward force to drive collective Schwann cell migration during nerve regeneration, identifying a dual role for N-cadherin in both adhesion and repulsion processes during Schwann cell collective migration.
2. 1. Cell Biology

   HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging

   John H. Day, Catherine Marin Della Santina ... Laurie A. Boyer
3. 1. Cell Biology

   Mecp2 Fine-tunes Quiescence Exit by Targeting Nuclear Receptors

   Jun Yang, Shitian Zou ... Xiaochun Bai
4. 1. Cell Biology
   2. Developmental Biology

   E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation

   Vartika Sharma, Nalani Sachan ... Ashim Mukherjee
5. 1. Cell Biology
   2. Neuroscience

   KIS counteracts PTBP2 and regulates alternative exon usage in neurons

   Marcos Moreno-Aguilera, Alba M Neher ... Carme Gallego

   KIS, a kinase upregulated in the developmental brain, phosphorylates the PTBP2 splicing complex and modulates alternative exon usage for proper synaptic spine emergence and maturation.
6. 1. Cell Biology

   Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

   Ang Li, Jianxun Yi ... Jingsong Zhou

   The distinct transcriptomic features of extraocular muscle satellite cells, partially mimicked by NaBu treatment, endow enhanced self-renewal and axon attraction, contribute to neuromuscular junction preservation during ALS progression.
7. 1. Cell Biology

   Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

   Simona Bolamperti, Hiroaki Saito ... Hanna Taipaleenmäki

   A novel mechanism underlying the regulation of osteoblast morphology, adherence, and migration that has implications in bone remodeling, regeneration, and response to the pharmacological effects of PTH treatment.
8. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between Neuropathy Target Esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
9. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association

   Marcel Proske, Robert Janowski ... Dierk Niessing

   Structural promiscuity in PURA protein, induced by patient mutations, impacts nucleic acid binding, unwinding, and subcellular localization, indicating why so many patients display the full disease spectrum of PURA syndrome.
10. 1. Cell Biology

    Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

    Mathieu C Husser, Nhat P Pham ... Alisa Piekny

    The split mNeonGreen system enables fast and efficient endogenous tagging in human iPSCs and facilitates the study of proteins in human stem cells and differentiated cells by live imaging.