2,123 results found
    1. Medicine
    2. Physics of Living Systems

    Synchronization in renal microcirculation unveiled with high-resolution blood flow imaging

    Dmitry Postnov, Donald J Marsh ... Olga Sosnovtseva
    High-resolution blood flow imaging confirms the presence of large, long-living synchronous clusters in renal microcirculation and reveals how vasoactive drugs affect synchronization properties.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Imaging single-cell blood flow in the smallest to largest vessels in the living retina

    Aby Joseph, Andres Guevara-Torres, Jesse Schallek
    By using a specialized camera that corrects for eye blur, millions of single-blood-cells are imaged, and their speed measured, as they travel through the largest-to-smallest vessels of the retina.
    1. Neuroscience

    In vivo imaging with a water immersion objective affects brain temperature, blood flow and oxygenation

    Morgane Roche, Emmanuelle Chaigneau ... Serge Charpak
    Brain temperature and oxygenation vary according to the imaging conditions during two-photon microscopy.
    1. Neuroscience

    Imaging of the pial arterial vasculature of the human brain in vivo using high-resolution 7T time-of-flight angiography

    Saskia Bollmann, Hendrik Mattern ... Jonathan R Polimeni
    Partial-volume effects were found to be the current limit to imaging pial arteries with MRI, not their slow blood flow, and therefore advanced acquisition techniques achieving resolutions below 200 µm in vivo provide a more complete picture of these vessels.
    1. Cell Biology

    Intelligent classification of platelet aggregates by agonist type

    Yuqi Zhou, Atsushi Yasumoto ... Keisuke Goda
    An intelligent method is developed to morphologically classify platelet aggregates by agonist type, which potentially opens a window on novel clinical diagnostics and therapeutics of thrombotic disorders.
    1. Neuroscience

    3D optogenetic control of arteriole diameter in vivo

    Philip J O'Herron, David A Hartmann ... Andy Y Shih
    The diameter of individual or multiple arterioles can be rapidly controlled with high spatiotemporal resolution using optogenetics, providing a technique for the direct manipulation of blood flow independently of neural activity or pharmacological agents.
    1. Cell Biology
    2. Developmental Biology

    Anisotropic organization of circumferential actomyosin characterizes hematopoietic stem cells emergence in the zebrafish

    Mylene Lancino, Sara Majello ... Anne Schmidt
    Emergence of hematopoietic stem cells from an aortic component is a unique phenomenon of cell extrusion, with no equivalent in cell biology, and which is adapted to environmental constraints exerted by endothelial cells and hemodynamics forces.
    1. Immunology and Inflammation
    2. Physics of Living Systems

    Label-free imaging of immune cell dynamics in the living retina using adaptive optics

    Aby Joseph, Colin J Chu ... Jesse Schallek
    Immune cell motility and vascular response are imaged in vivo and label free in the CNS for the first time, using high-resolution phase-contrast adaptive optics retinal imaging.
    1. Biochemistry and Chemical Biology

    Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing

    Dibesh Thapa, Joäo de Sousa Valente ... Susan D Brain
    Cold detecting thermoreceptor TRPM8's signalling is diminished with ageing which leads to an impaired response to cold observed in ageing.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Male rat leukocyte population dynamics predict a window for intervention in aging

    Hagai Yanai, Christopher Dunn ... Isabel Beerman
    Rat blood profiles support non-linear aging with distinct trajectory shifts, and these profiles could be used to predict non-overt illness in rats or aging intervention efficacy.

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