11 results found
    1. Ecology
    2. Plant Biology

    Wild cereal grain consumption among Early Holocene foragers of the Balkans predates the arrival of agriculture

    Emanuela Cristiani, Anita Radini ... Dušan Borić
    A consistent pattern of consumption of Triticeae tribe grasses documented in the Danube Gorges of the Balkans since the Early Mesolithic might have facilitated a quick uptake of domesticated cereals due to a developed cultural taste and specific stone tool processing technology.
    1. Stem Cells and Regenerative Medicine

    Sox9+ messenger cells orchestrate large-scale skeletal regeneration in the mammalian rib

    Stephanie T Kuwahara, Maxwell A Serowoky ... Francesca V Mariani
    Large-scale skeletal regeneration requires Hh signaling in Sox9+ lineage cells to coordinate callus formation and bone repair.
    1. Immunology and Inflammation
    2. Medicine

    Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling

    Kai Sun, Chun Wang ... Gabriel Mbalaviele
    Inflammatory responses mediated by gasdermins are important for adequate fracture healing.
    1. Evolutionary Biology

    A Bayesian approach to dynamic homology of morphological characters and the ancestral phenotype of jawed vertebrates

    Benedict King, Martin Rücklin
    The ancestor of all known jawed vertebrates possessed a maxilla and premaxilla and was similar in morphology to the 'maxillate placoderms' from China.
    1. Ecology
    2. Genetics and Genomics

    Adulis and the transshipment of baboons during classical antiquity

    Franziska Grathwol, Christian Roos ... Gisela H Kopp
    The first sequenced mitogenome of a mummified non-human primate connects an Egyptian baboon dated to ca. 800–540 BCE to modern baboon populations in Eritrea, Ethiopia, and eastern Sudan, providing evidence for Egyptian–Adulite trade centuries earlier than current archaeological evidence.
    1. Developmental Biology

    Clec11a/osteolectin is an osteogenic growth factor that promotes the maintenance of the adult skeleton

    Rui Yue, Bo Shen, Sean J Morrison
    A C-type lectin domain protein is an anabolic growth factor that promotes mesenchymal progenitors in the bone marrow to differentiate into bone cells to maintain skeletal bone mass throughout adult life.
    1. Stem Cells and Regenerative Medicine

    Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation

    Rubens Sautchuk, Brianna H Kalicharan ... Roman A Eliseev
    Promoter studies identified BMP/Smad signaling as a transcriptional regulator of Ppif gene encoding cyclophilin D, a component of the mitochondrial permeability transition pore, and gain- and loss-of-function experiments determined how such regulation affects osteogenic differentiation.
    1. Evolutionary Biology

    New fossils of Australopithecus sediba reveal a nearly complete lower back

    Scott A Williams, Thomas Cody Prang ... Lee R Berger
    Newly recovered lumbar vertebrae belonging to Malapa Hominin 2, an adult female of the fossil hominin species Australopithecus sediba, demonstrate that this individual was adapted to upright posture and bipedal locomotion but also had adaptations for climbing in trees.
    1. Cell Biology
    2. Medicine

    Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and β-catenin-OPG/Jagged1 pathway

    Yongli Qin, Jumpei Shirakawa ... Baohong Zhao
    Malat1 is a key skeletal regulator, unveiling how lncRNAs integrate cellular crosstalk and molecular networks to regulate bone remodeling and regeneration, establishing a novel paradigm in tissue homeostasis and repair.
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete

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