Browse our latest Cell Biology articles

Page 129 of 318
    1. Cell Biology
    2. Microbiology and Infectious Disease

    HIV-1 Infection: You can keep your coat on

    Gregory J Bedwell, Alan N Engelman
    High-resolution imaging techniques reveal new insights into the actions of the retrovirus HIV-1 inside host cells.
    Version of Record
    Insight
    1. Cancer Biology
    2. Cell Biology

    A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

    Alvaro Gonzalez Rajal, Kamila A Marzec ... Andrew Burgess
    Platinum chemotherapy resistance is a complex process involving multiple signalling pathways and a novel, non-genetic, cell cycle-dependent mechanism that promotes tumour regrowth and highlights potential complications for combination therapies in human lung adenocarcinoma.
    1. Cancer Biology
    2. Cell Biology

    PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

    Allen T Yu, Carmen Berasain ... David L Spector
    PHAROH lncRNA is upregulated in hepatocellular carcinoma and functions by sequestering the translational suppressor TIAR via a 71 nucleotide hairpin to regulate c-MYC translation.
    1. Cell Biology
    2. Physics of Living Systems

    Flagellar energetics from high-resolution imaging of beating patterns in tethered mouse sperm

    Ashwin Nandagiri, Avinash Satish Gaikwad ... Ranganathan Prabhakar
    Calculations of flagellar energetics from beating patterns in sperm reveal that internal dissipation by dynein motors and other passive structures within the flagellum significantly exceeds external hydrodynamic dissipation.
    1. Cell Biology

    Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells

    Maxence Le Vasseur, Jonathan Friedman ... Jodi Nunnari
    OCIAD1 associates with prohibitin assemblies and regulates the proteolytic processing and stability of the catalytical Complex III subunit cytochrome c1.
    1. Cell Biology
    2. Developmental Biology

    Combinatorial deployment of F-actin regulators to build complex 3D actin structures in vivo

    Yi Xie, Rashmi Budhathoki, J Todd Blankenship
    Phasic microfilament behaviors of the growth and stabilization of cortical actin caps are driven by distinct combinations of actin regulatory proteins, which display features of a deep competition for G-actin.
    1. Cell Biology

    Starvation-induced regulation of carbohydrate transport at the blood–brain barrier is TGF-β-signaling dependent

    Helen Hertenstein, Ellen McMullen ... Stefanie Schirmeier
    Detailed analysis of transporter expression and glucose uptake rates shows that carbohydrate import at the blood–brain barrier is adapted via TGF-βsignaling-dependent transcriptional regulation of carbohydrate transporters to protect the brain form effects of nutrient shortage.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

    Wan Hua Li, Ke Huang ... Yong Juan Zhao
    The first-in-class cell-permeant fluorescent probe provides direct and visual evidence of SARM1 activation in axonal degeneration and identified the first covalent, allosteric inhibitor of SARM1 acting on the NAD-binding pocket in the ARM domain.
    1. Cell Biology
    2. Computational and Systems Biology

    Artistoo, a library to build, share, and explore simulations of cells and tissues in the web browser

    Inge MN Wortel, Johannes Textor
    By letting users build interactive simulations directly in a web browser, Artistoo unlocks new ways to communicate, teach, and collaborate in computational biology research.
    1. Cell Biology

    A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin-induced corpus luteum regression

    Dianrong Li, Jie Chen ... Xiaodong Wang
    A phosphorylation of receptor interacting RIPK3 switches its pro-necroptosis function to apoptosis that promotes luteal regression which induced by Prostaglandin F2alpha.