João Paulo Portela Catani, Anouk Smet ... Thorsten U Vogel
N2 neuraminidases from human H3N2 viruses from 2009 until 2017 can be subdivided into four antigenic groups, with amino acid substitutions near the catalytic site more likely impacting neuraminidase inhibition.
Timothy A Bates, Mila Trank-Greene ... Fikadu G Tafesse
ESAT-6, a virulence factor of Mycobacterium tuberculosis, dimerizes at neutral pH and transitions to oligomers under acidic pH similar to that of lysosome, helping the bacterium evade host defense mechanisms.
A detailed characterizations of EDTA-treated Candida albicans cells both in vitro and pre-clinical models led to discovery of a potential live whole-cell vaccine against fungal infections.
Interplay between multiple Legionella pneumophila effector proteins lead to spatial and temporal regulation of the host Rab10 localization to the bacterial vacuole by controlling noncanonical ubiquitin modifications.