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The yeast syntaxin homolog Tlg2p-residing sub-compartment within the trans-Golgi network is the primary endocytic-accepting region that serves as an early/sorting compartment.

Androgen receptor activation modifies B cell frequencies and functionality, accompanied by weight gain in female mice exposed to human PCOS IgG, highlighting the unrecognized involvement of B cells in PCOS autoimmune comorbidities despite their absence not preventing PCOS phenotype development.

While recognizing study design limitations, the lack of association between household close range proximity events and SARS-CoV-2 transmission, suggests that aerosol transmission may play a larger role than droplet transmission in the household.

HIV-1 infection activates the human CARD8 inflammasome via innate immune recognition of HIV-1 viral protease activity.

Combination of primary brain culture and single-cell RNA sequencing in brain organoids identifies microglia as the main target of rubella virus infection.

Understanding protein kinase regulation by activation loop autophosphorylation depends on a critical assessment of experimental design, execution, and interpretation.

Proteomic analysis in a novel cell-free system for the study of mitophagy, identifies candidate proteins involved in the enforcement of clonal, maternal inheritance of mitochondria and mitochondrial genes in mammals.

Metformin selectively improves bone healing of three types of bone injuries in hyperglycemic but not in normoglycemic mice.

Novel disease pathways underlie disease pathogenesis in Kelch-related nemaline myopathy through proteomic remodeling.