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HIV transmissions into intervention communities from control communities in the Botswana/Ya Tsie trial were similar to the reverse at baseline, and 10 times more common post-baseline, concordant with a predicted benefit of a universal test-and-treat HIV prevention intervention.

Horizontal gene transfer can potentially merge genomes from distinct bacterial species, but isolation in different hosts creates a physical barrier to gene flow.

Augmentation of progestin signaling promotes testis development and spermatogenesis independent from andorgen signaling in zebrafish.

259 CpGs associated with season of conception in rural Gambians constitute a valuable resource for investigating epigenetic mechanisms linking early exposures to lifelong health and disease.

Human somites are formed in organoids from human pluripotent stem cells.

The m⁶A reader YTHDF2 negatively regulates retinal ganglion cell dendrite branching through destabilizing its m⁶A-modified target mRNAs which control dendrite development and maintenance, and Ythdf2 conditional knockout in retina improves visual acuity and alleviates acute ocular hypertension-induced glaucoma in mice.

Optical recordings from L5 cortical pyramidal neurons expressing mitochondria-targeted Ca²⁺ indicator, mitoGCaMP6m, reveal compartment-specific mitochondrial responses to spike firing and synaptic activity.

The integration of biplanar X-ray videos with 3D X-ray particle tracking revealed that fish use a combination of intraoral 'central jet' waterflow pattern and inertia to guide food toward the digestive tract during suction feeding.

Deletion of Alzheimer’s disease risk gene TREM2 augments sensitivity to the purinergic agonist ADP, leading to increased Ca²⁺ influx and reduced directional migration in human induced pluripotent stem cell-derived microglia.

RNA-binding proteins use both translational activation and repression of key molecular determinants to post-mitotically sculpt the identity and connectivity of developing mouse neocortex in an area-specific manner.