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Page 928 of 1,838
    1. Cell Biology
    2. Medicine

    Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8

    Hsiang-Chun Chang, Jason Solomon Shapiro ... Hossein Ardehali
    Mammalian cellular iron homeostasis and the maturation of the cytosolic iron sulfur cluster proteins are dependent on the mitochondrial protein import machinery.
    1. Developmental Biology

    Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

    Naokazu Inoue, Yoshihisa Hagihara, Ikuo Wada
    Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.
    1. Neuroscience

    Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

    Kang-Ying Qian, Wan-Xin Zeng ... Xia-Jing Tong
    Male pheromone environment increases the cholinergic synaptic transmission at the neuromuscular junction in Caenorhabditis elegans hermaphrodites during development, decreasing hermaphrodites' locomotion activity and promoting mating efficiency.
    1. Developmental Biology

    Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

    Georges Raad, Fabrizio Serra ... Valerie Grandjean
    Predisposition to obesity-associated diseases is dependent on the ancestors' diet.
    1. Evolutionary Biology

    Striking parallels between dorsoventral patterning in Drosophila and Gryllus reveal a complex evolutionary history behind a model gene regulatory network

    Matthias Pechmann, Nathan James Kenny ... Siegfried Roth
    Crucial functions of Toll signalling during dorsoventral axis formation might have evolved convergently in flies and crickets.
    1. Immunology and Inflammation
    2. Neuroscience

    Development and characterization of a chronic implant mouse model for vagus nerve stimulation

    Ibrahim T Mughrabi, Jordan Hickman ... Stavros Zanos
    Long-term, dose-controlled vagus nerve stimulation (VNS) is feasible in mice using a multi-lab validated implantation procedure, allowing therapeutic testing of VNS in many disease models.
    1. Neuroscience

    Local projections of layer Vb-to-Va are more prominent in lateral than in medial entorhinal cortex

    Shinya Ohara, Stefan Blankvoort ... Menno P Witter
    The connection from layer Vb-to-Va neurons, a key component of the canonical hippocampal-cortical output circuit, which is allegedly crucial for memory consolidation, is relatively stronger in lateral entorhinal cortex compared with the medial entorhinal cortex, thus suggesting different operating principles.
    1. Neuroscience

    Slowing the body slows down time perception

    Rose De Kock, Weiwei Zhou ... Martin Wiener
    The perception of time is influenced by movement environments, with slower movements associated with shorter perceived time intervals.
    1. Microbiology and Infectious Disease

    Functional insights from a surface antigen mRNA-bound proteome

    Larissa Melo do Nascimento, Franziska Egler ... Esteban Erben
    A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation

    Emma Carley, Rachel M Stewart ... Megan C King
    Forces stemming from cell-matrix adhesions, but not cell-cell adhesions, are directly transmitted to the nuclear lamina to regulate epidermal cell fate.