Browse our Research Articles

Page 461 of 1,383
    1. Developmental Biology
    2. Evolutionary Biology

    Cnidarian hair cell development illuminates an ancient role for the class IV POU transcription factor in defining mechanoreceptor identity

    Ethan Ozment, Arianna N Tamvacakis ... Nagayasu Nakanishi
    Developmental genetics of sea anemone mechanosensory neurons provides insights into the deep evolutionary history of mechanoreceptor development in animals.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells

    Wai Hoe Ng, Elizabeth K Johnston ... Xi Ren
    An induced pluripotent stem-cell-based, human heart and lung co-differentiation model reveals their shared signaling requirement and enables investigation of their developmental mutual interaction and tissue boundary formation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Vaccine-induced COVID-19 mimicry syndrome

    Eric Kowarz, Lea Krutzke ... Rolf Marschalek
    The Spike gene expressed by the vector-based vaccine Vaxzevria bears the risk of cryptic splicing, which in turn may lead to cellular production of soluble, instead of membrane-anchored, Spike protein variants.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A DCL3 dicing code within Pol IV-RDR2 transcripts diversifies the siRNA pool guiding RNA-directed DNA methylation

    Andrew Loffer, Jasleen Singh ... Craig S Pikaard
    Double-stranded precursors of siRNAs involved in RNA-directed DNA methylation have initiating sequences and overhangs imparted by the RNA polymerases that synthesize them, programming alternative dicing reactions that diversify the siRNA pool.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

    Rachael E Barton, Lucia F Massari ... Adèle L Marston
    Meiotic recombination and chromosome segregation require the establishment of chromatin boundaries by the acetyltransferase Eco1, which anchors both chromatin loops and cohesion.
    1. Computational and Systems Biology
    2. Neuroscience

    An image reconstruction framework for characterizing initial visual encoding

    Ling-Qi Zhang, Nicolas P Cottaris, David H Brainard
    A computational model of the initial visual encoding together with Bayesian image reconstruction quantifies how that encoding, combined with the statistical regularities of natural images, shapes key aspects of visual perception.
    1. Immunology and Inflammation

    Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

    Ruchi Roy, Janet Zayas ... Sasha H Shafikhani
    Therapeutic potential of CCL3 for the treatment of diabetic foot ulcers if it is applied topically after the surgical debridement.
    1. Cell Biology
    2. Immunology and Inflammation

    Functional visualization of NK cell-mediated killing of metastatic single tumor cells

    Hiroshi Ichise, Shoko Tsukamoto ... Michiyuki Matsuda
    Live imaging of the duel of an NK cell versus a metastatic cancer cell on pulmonary epithelial cells reveals a novel survival tactics adopted by cancer cells.
    1. Neuroscience

    Laminar microcircuitry of visual cortex producing attention-associated electric fields

    Jacob A Westerberg, Michelle S Schall ... Jeffrey D Schall
    Simultaneous sampling of electrical voltages outside the brain with neural signals in the cerebral cortex reveals how electrical currents in mosaics of cortical columns produce an electrical signal that can be measured noninvasively to assess the allocation of attention.
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells

    Daniel E Morales-Mantilla, Bailee Kain ... Katherine Y King
    Infusion of hematopoietic stem and progenitor cells rescues mice from lethal Group A streptococcal sepsis.