Timely regulation of growth cone dynamics, including filopodial and cytoskeletal rearrangements through phosphorylation signals from glial cells, shapes the photoreceptor axon targeting.
Helen M Tauc, Imilce A Rodriguez-Fernandez ... Heinrich Jasper
Global, multi-angled genetic analyses identified an age-associated loss of stem cell lineage fidelity that was linked to changes in polycomb regulation in the Drosophila intestinal epithelium.
Manuela Kramer, Melvin Rodriguez-Heredia ... Guy Thomas Hanke
The regulatory switch from protection to assimilation, which plants use to exploit natural, fluctuating light, involves movement of the enzyme ferredoxin:NADP(H) oxidoreductase between chloroplast membrane complexes.
Theory explains how transport of gene expression vortices by cell advection may cause intermingled defective and normal segments along the body axis during resynchronization experiments in the zebrafish segmentation clock.
Jamie L Courtland, Tyler WA Bradshaw ... Scott H Soderling
Cellular etiology of a human WASH complex mutation in mice reveals its specific roles in neuronal organelle trafficking and a surprising role in motor impairments.
The development of complex motion processing in higher-level visual cortex involves functional changes in primary visual cortex, indicating coordinated development in multiple nodes of the visual hierarchy.
Aditya Raghunandan, Antonio Ladron-de-Guevara ... Douglas H Kelley
A new tracer infusion method is used to confirm that pulsatile cerebrospinal fluid transport into the brain occurs naturally and is driven by the cardiac cycle, not by tracer injection.
Mid-gestational exposure to maternal immune activation drives a sequence of transcriptional signatures and developmental pathology in embryonic mouse cortex, culminating in altered lamination and cellular lineage specification.
Daniel B Larremore, Bailey K Fosdick ... Yonatan H Grad
Integrating over multiple forms of statistical uncertainty associated with serological surveys can improve serosurvey design while also enabling that uncertainty to be appropriately propagated through epidemiological models.