Browse our Research Articles

MRGPRD and MRGRPX1 are co-expressed in primate DRG neurons, but β-alanine and BAM8-22, preferentially activate CMH-subclasses, and co-activating different cutaneous nociceptors by pruritogens does not change itch sensation to pain.

Tyramine-dependent signaling triggers decondensation of neuronal RNP components and rapid translation activation of target mRNAs.

A novel multi-omics framework revealed the taxonomic contribution to microbiota oxalate, demontrated O. formigenes as the dominating taxon transcriptionally, and identified specific IBD cohort at risk for oxalte toxicity.

Sensing of ligands by chemoreceptors of Escherichia coli not only causes changes in the rotational bias of the flagellar motors but also increases motor speed via temporary recruitment of stators.

The effect of genetic variation on gene expression can be specific down to the level of individual cells.

A genome-wide catalog of the regulatory effects of variants that separate modern humans from archaic humans.

Drosophila macrophages are a heterogeneous population of cells containing subpopulations with enhanced responses to injury that display considerable variation in their abundance across development.

The general transcription elongation factor NusG functions as an intrinsic termination factor in Bacillus subtilis and together with NusA coordinates global gene expression including the motility regulon.

Heterogeneity in cytoplasmic calcium concentration alongside B cell activation and differentiation is measured intravitally using an interdisciplinary imaging approach and novel numerical analysis.

A combination of equilibrium and nonequilibrium molecular dynamics simulations is an effective tool to study allosteric communications in ultrafast enzymes that show little or no conformational changes.