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Open science and consensus antibody validation protocols can identify high-quality, renewable antibodies for the ~50% of the human proteome currently covered, enabling robust and reproducible biomedical research.

Researchers and administrators can integrate reproducible research and open science practices into daily practice at their research institutions by adapting research assessment criteria and program requirements, offering training, and building communities.

Irregular sleep-wake patterns are associated with higher mortality risk, including mortality due to cancer and cardiovascular disease.

A computational approach based on connectivity hyperalignment can estimate individualized functional topography with high fidelity across movie contents, scanners, protocols, and languages.

On different bacterial diets, which also serve as different environments for Caenorhabditis elegans, specific sensory neurons and insulin-like peptides integrate food-derived signals to modulate oocyte biology, and hence reproduction.

Metabolomic analysis shows how genome-wide changes in gene expression propagate to and affect the metabolomes of an organism during adaptation.

The photoreceptor tetraspanin protein ROM1 contributes to the formation of light-sensitive 'disc' membranes, but it can be functionally replaced by an excess of its homologous binding partner PRPH2.

Polymorphic residues of a vacuolar Ca²⁺ sensor site in TPC1 channels differ between species of Brassicacea and Fabaceae and lead to distinct TPC1 gating behavior.