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    1. Genetics and Genomics

    Polygenic Screening: What’s the use?

    Jason M Fletcher, Yuchang Wu, Qiongshi Lu
    A theoretical framework predicts that using polygenic screening to select embryos against traits that depend on many genes has few benefits.
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    1. Biochemistry and Chemical Biology

    Chaperones: Aggregation in the spotlight

    Zihao Wang, Miranda Collier, Justin Benesch
    New findings clarify apparently conflicting results about how molecular agents that preserve protein integrity prevent harmful, dense aggregates from forming.
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  1. Image of Oded Rechavi

    Scientists on Social Media: Oded Rechavi

    Meet the king of science memes.
    1. Cancer Biology
    2. Genetics and Genomics

    Risk Modeling: Predicting cancer risk based on family history

    Michelle F Jacobs
    A new software package provides more accurate cancer risk prediction profiles and has the ability to integrate more genes and cancer types in the future.
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    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Membrane Proteins: Pain or gain?

    Valeria Kalienkova
    The 3D structures of a membrane protein called TMEM120A suggest that it may act as an enzyme in fat metabolism rather than as an ion channel that senses mechanical pain.
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    1. Cancer Biology
    2. Medicine

    Cancer Immunotherapy: A promising platform for predicting toxicity

    Maria Ochoa de Olza
    Organ-on-chip approaches could help researchers to better predict the toxicity of cancer immunotherapy drugs.
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  2. Research Culture: Creating SPACE to evolve academic assessment

    Ruth Schmidt, Stephen Curry, Anna Hatch
    The San Francisco Declaration on Research Assessment (DORA) has developed a new tool called SPACE to support universities and institutions working to improve the assessment of research.
    1. Ecology

    Ecosystem Resilience: Mapping the future for coral reefs

    Line K Bay, Emily J Howells
    The ability of corals to adapt to global warming may involve trade-offs among the traits that influence their success as the foundational species of coral reefs.
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    1. Microbiology and Infectious Disease

    Parasite Transmission: A two-stage solution

    Fabien Guegan, Luisa Figueiredo
    The parasite that causes African sleeping sickness can be transmitted from mammals to tsetse flies in two stages of its lifecycle, rather than one as was previously thought.
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    1. Epidemiology and Global Health
    2. Immunology and Inflammation

    Inflammation: Western diet shifts immune cell balance

    Christina M Bergey
    The immune cells of macaques fed a Western-like diet adopt a pro-inflammatory profile.
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