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    1. Computational and Systems Biology
    2. Neuroscience

    Meta-Research: Dataset decay and the problem of sequential analyses on open datasets

    William Hedley Thompson, Jessey Wright ... Russell A Poldrack
    Open data provides an opportunity to perform new analyses on preexisting data, but trade-offs are required to limit an increase in false positives.
    1. Neuroscience

    Motor Performance: Acetylcholine in action

    Erin M Wall, Sarah C Woolley
    The neurotransmitter acetylcholine influences how male finches perform courtship songs by acting on a region of the premotor cortex called HVC.
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    1. Cancer Biology
    2. Genetics and Genomics

    Tumor Evolution: Finding the mutations that drive resistance

    Nadine Bley
    Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach.
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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Science Forum: SARS-CoV-2 (COVID-19) by the numbers

    Yinon M Bar-On, Avi Flamholz ... Ron Milo
    Key numbers about the biology of the SARS-CoV-2 virus and the infection of a single human host by the virus have been compiled from the peer-reviewed literature.
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Immunogenetics: Untangling the immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca
    Interactions between immune cell receptors and proteins that determine disease susceptibility shed light on how different arms of the immune system are involved in three viral infections and Crohn's disease.
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    1. Cell Biology

    Bone: A role for fat precursors in the marrow

    Noriaki Ono
    A group of cells that can become adipocytes controls the formation of blood vessels in the bone marrow, and also regulates the differentiation of resident mesenchymal progenitor cells.
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  1. Research Culture: A Selection of Articles

    Edited by Julia Deathridge
    Research culture needs to be improved for the benefit of science and scientists.
    1. Microbiology and Infectious Disease

    Bacteria: Driving polar growth

    Neeraj Dhar
    Profiling the phenotype of 200,000 mutants revealed a new cofactor that may help a group of rod-shaped bacteria elongate and grow.
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    1. Medicine

    Drug Discovery: From worms to fish to mice

    Guy M Benian, Hyojung J Choo
    An multi-species approach can be used to identify small molecules with properties that might prove useful for the treatment of some neuromuscular diseases.
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    1. Stem Cells and Regenerative Medicine

    Stem Cells: Encouraging cartilage production

    H Scott Stadler
    A long non-coding RNA called GRASLND is essential to help stem cells create stable cartilage.
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