3,654 results found
    1. Cell Biology
    2. Plant Biology

    Members of the ELMOD protein family specify formation of distinct aperture domains on the Arabidopsis pollen surface

    Yuan Zhou, Prativa Amom ... Anna A Dobritsa
    Pollen aperture patterning in Arabidopsis is controlled by members of the ELMOD protein family, whose expression levels in developing pollen lineage are tightly regulated.
    1. Neuroscience

    Early life experience sets hard limits on motor learning as evidenced from artificial arm use

    Roni O Maimon-Mor, Hunter R Schone ... Tamar R Makin
    Biological- or artificial-arm experience during early development has a significant effect on artificial-arm motor control in adulthood, providing evidence for limited sensorimotor plasticity beyond childhood.
    1. Neuroscience

    POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons

    Rajae Talbi, Todd L Stincic ... Víctor M Navarro
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence

    Pramod K Jangir, Lois Ogunlana ... Craig R MacLean
    Resistance genes that spread as a result of the use of an antimicrobial peptide (colistin) in agriculture (MCR) protect bacteria against key components of human and animal immune systems.
    1. Chromosomes and Gene Expression

    Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones

    Nina Kirstein, Alexander Buschle ... Aloys Schepers
    Replication origins are established throughout the genome with the exception of transcribed genes, and the local chromatin composition likely modulates the density of ORC and MCM as well as origin activation.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Analysis of the crystal structure of an active MCM hexamer

    Justin M Miller, Buenafe T Arachea ... Eric J Enemark
    Building on previous work (Froelich et al., 2014), we present the X-ray crystal structure of an active MCM hexamer, which suggests a mechanism for MCM regulation and demonstrates a key interaction between the major domains.
    1. Cancer Biology
    2. Immunology and Inflammation

    Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

    Sofia V Krasik, Ekaterina A Bryushkova ... Ekaterina O Serebrovskaya
    BCR profiling of tumor infiltrating B cells alongside with circulating and lymph node-resident B cells deepens understanding of their unique properties.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes

    Carolina Ortiz-Cordero, Alessandro Magli ... Rita CR Perlingeiro
    The combined use of NAD+ with ribitol or ribose potentiates the rescue of α-dystroglycan functional glycosylation in FKRP-mutant patient-specific iPSC-derived myotubes, representing potential novel treatments for FKRP muscular dystrophies.
    1. Immunology and Inflammation

    RAG1 and RAG2 non-core regions are implicated in leukemogenesis and off-target V(D)J recombination in BCR-ABL1-driven B-cell lineage lymphoblastic leukemia

    Xiaozhuo Yu, Wen Zhou ... Yanhong Ji
    Non-core RAG regions, especially RAG1, maintain V(D)J recombination accuracy and genomic stability, reducing malignant characteristics and off-target recombination in BCR-ABL1+ B-cell acute lymphoblastic leukemia.
    1. Cancer Biology
    2. Ecology

    Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe

    Daniel Garcia-Souto, Alicia L Bruzos ... Jose MC Tubio
    Genome sequencing analysis dissects the origins and evolution of cancer transmission between clam species in the Seas of Southern Europe.

Refine your results by:

Type
Research categories