An inoculation experiment shows phyllosphere microbiome plays an important role in invader Ageratina adenophora population establishment by killing seedlings at very early growth stage.
Javier I Ottaviani, Virag Sagi-Kiss ... Gunter GC Kuhnle
The reliance on food composition databases for the assessment of dietary intake is unreliable and results in a large bias when investigating the associations between diet and disease risk.
Depleting senescent osteoclasts using the senolytic drug Navitoclax (ABT263) can reduce sensory innervation in the endplate and attenuate low back pain, thus representing a potent therapy for treating spinal pain.
Harshvardhan Gazula, Henry FJ Tregidgo ... Juan E Iglesias
New open-source software enables, for the first time, extraction of quantitative information from brain dissection photographs that are routinely taken at brain banks for archiving purposes but otherwise not exploited.
Katarzyna Drożdżyk, Martina Peter, Raimund Dutzler
Structural studies revealing the organization of assemblies consisting of CALHM2 and CALHM4 subunits provide insight into the mechanism of heteromerization of large pore channels.
The pseudokinase Tribbles1 is expressed in human monocytes after mycobacterial challenge and can be manipulated to be host protective against mycobacterial infection, due to control of innate immune cell function, in a zebrafish tuberculosis model.
A combination of cryo-electron microscopy, structure prediction, and evolutionary analyses reveal several functional states of the dynamic protein translocation machinery at the mammalian endoplasmic reticulum.
Marie Breeur, George Stepaniants ... Vivian Viallon
A computational method based on optimal transport enables state-of-the-art alignment between untargeted metabolomic studies and is evaluated on cord blood and cancer datasets.
