The small ubiquitin-like modifier system directly regulates components of the chloroplast protein import apparatus, that is, TOC proteins, to control chloroplast biogenesis and plant development.
Isabella Farhy-Tselnicker, Matthew M Boisvert ... Nicola J Allen
RNA sequencing and genetic mouse models reveal that transcriptional changes to astrocytes in the developing cortex are not intrinsic but influenced by their environment and determine that expression of astrocyte synapse-regulating genes and neuronal synaptogenesis is modulated by ongoing astrocyte-neuron communication.
Convergent structural and functional brain deficits associated with dyslexia were found in left superior temporal gyrus across languages, however, language-specific deficits were also identified.
Luca Tirinato, Maria Grazia Marafioti ... Joao Seco
Lipid Droplet accumulation is a fingerprint shared by different human cancer radioresistant cells and their biogenesis strongly depend on FTH1 presence.
Certain mutational signatures vary in their contribution to genetic variation across the yeast phylogeny due to genetically encoded natural mutator phenotypes whose activity can be directly measured in the lab.
High-throughput and ultra-stable magnetic tweezers reveal that Remdesivir induces a long-lived backtrack pause upon incorporation by the coronavirus polymerase, and SARS-CoV-2 is able to evade interferon-induced antiviral ddhCTP.
Jingjing Zang, Matthias Gesemann ... Stephan CF Neuhauss
Circadian expression of cone visual transduction genes and corresponding proteins correlates with circadian changes in photoresponse kinetics and visual behavior, linking circadian gene expression with physiological and behavioral rhythmicity.
Anitha P Govind, Okunola Jeyifous ... William N Green
Neuronal activity triggers the dispersal of the Golgi into dendritic Golgi satellites, leading to reshaping of the neuronal surface glycoproteome through processing of glycans to mature, sialic acid-containing forms.
Carriage of MDR S. Typhi H58 sublineages that also cause acute disease provides understanding of the transmission dynamics of typhoid fever and maintenance of local pathogen populations in Kenya children.
