Browse our latest research

Rare, virus-specific immune cells in human blood are automatically identified by machine learning algorithm T-REX and characterized for signature features needed for tracking and isolation.

Time-course phosphoproteomics reveals that selective dephosphorylation is critical for directing the MI/MII transition and that, through its inherent phospho-threonine preference, PP2A-B55 imposes specific phosphoregulated behaviors that distinguish the two meiotic divisions.

The McsB kinase is critical for protein quality control in Gram-positive bacteria, assembling a gated phosphorylation chamber during heat-shock conditions to selectively mark misfolded proteins for degradation.

Image3C is a new image-based analysis of cell population composition for research organisms in which detailed cellular phenotypes are unknown or for which species-specific reagents are not available.

Repertoires of autoreactive murine follicular T helper cells synchronize transiently within one individual.

Genetic analyses revealed the remarkable plasticity of mesodermal cells to differentiate across the germ layers to form insulin-producing β-cells, which are normally of endodermal origin.

Human yolk sac-like cells, which share characteristics with the post-implantation human hypoblast, can model the interaction between the epiblast and hypoblast that occurs during early human development.

Mosquitoes may be likely to adapt to climate warming given their short life cycles and strong temperature sensitivity, but key data gaps identified here constrain current estimates of adaptive potential.

Neurofibromatosis type 1 gene (NF1) signaling is causally linked to the acquisition of a mesenchymal gene expression program in gliomas through the regulation of the AP-1 transcription factor FOSL1.

Allele differences in gene expression dynamics are associated with insertions and deletions and are caused in part by multiple variants within the same promoter region.