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An inference paradigm for extracting neuronal correlations from two-photon imaging data, without requiring intermediate spike deconvolution, provides significant performance gains over existing methods as demonstrated by theoretical analysis, simulation studies, and real-data applications.

Analysis of mutant cells combined with biochemical experiments reveals that CEP78 is recruited to the centrosome by CEP350 and regulates ciliogenesis and ciliary length control through CP110-dependent and CP110-independent mechanisms, respectively.

The eIF3 translation initiation complex exerts specific regulation on neuronal protein levels by targeting mRNAs with GC-rich 5' UTR.

Potent and low-cost Nanosota-1 drug candidates block SARS-CoV-2 infections in vitro and in animal models and act preventively and therapeutically.

Psychometric measures reveal that, contrary to common assumption, rats have good visual form discrimination capacity under red and even far-red illumination.

Large-scale genetic surveillance of malaria implemented by National Malaria Control Programmes informs public health decision makers about the spread of strains resistant to antimalarials.

In addition to the well-established involvement of descending neural tracts, the left-right side-specific endocrine mechanism may contribute to signaling from injured brain to spinal motor circuits.

The three-dimensional and asymmetrical transformations undergone by the zebrafish linear heart tube during looping morphogenesis are under the control of cardiac-intrinsic cues.

Context-based object recognition causally relies on both scene- and object-selective cortex, with scene-selective cortex generating expectations (at 160-200 ms after onset) that disambiguate object representations in object-selective cortex (at 260-300 ms after onset).

A mouse model where the splicing factor SRSF1 was prevented from accumulating in the cytoplasm revealed reduced translation of thousands of mRNAs and postnatal phenotypes particularly affecting multiciliated cells.