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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Bacterial Warfare: Toxins, mutations and adaptations

    Maarten De Jong, Neal M Alto
    The toxins that some bacteria secrete to kill off rival species can also generate mutations that help toxin-resistant populations adapt to new environments.
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    1. Evolutionary Biology

    Experimental Evolution: Failure to progress

    Duncan Greig, Jasmine Ono
    Experiments on yeast cells that are hosts to a killer virus confirm that natural selection can sometimes reduce fitness.
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    1. Cell Biology
    2. Genetics and Genomics

    Aging: Unite to predict

    Meeraj Kothari, Daniel W Belsky
    Integrating the analysis of molecular data from different sources may improve our understanding of the effects of biological aging.
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    1. Cell Biology
    2. Developmental Biology

    Cell Cycle: Deciding when to exit

    Joy H Meserve, Robert J Duronio
    A new imaging approach can distinguish between cells destined to stop proliferating and those committed to re-entering the cell cycle in live animals.
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    1. Neuroscience

    Thalamocortical Synapses: Like a clock in the rabbit's visual cortex

    Frédéric Chavane, Diego Contreras
    Three rules govern the connectivity between neurons in the thalamus and inhibitory neurons in the visual cortex of rabbits.
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    1. Neuroscience

    In Vivo Models: Visualizing traumatic brain injuries

    Marc Ekker
    Zebrafish larvae models can be used to study the link between seizures and the neurodegeneration that follows brain trauma.
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    1. Neuroscience

    Memory: A divalent boost from magnesium

    Willem J Laursen, Paul A Garrity
    Enhanced levels of dietary magnesium improve long-term memory in fruit flies.
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    1. Computational and Systems Biology

    Cardiac Optogenetics: A move in the light direction

    Eike M Wülfers, Franziska Schneider-Warme
    Computer simulations show how low-intensity illumination can be used to terminate cardiac arrhythmias.
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    1. Structural Biology and Molecular Biophysics

    Small-Molecule Inhibitors: Disrupting enzyme fluidity

    Ganesh Srinivasan Anand
    A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton’s tyrosine kinase and alter the conformation of this enzyme.
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    1. Biochemistry and Chemical Biology
    2. Medicine

    Bone Hormones: Survival of the glycosylated

    Harry C Blair, Paul H Schlesinger
    Osteocalcin is a bone matrix protein that acts like a hormone when it reaches the blood, and has different effects in mice and humans.
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