The partial success of an attempt to repeat findings in cancer biology highlights the need to improve study designs for preclinical research into metastasis and the targeting of cancer cells.
New methods to directly visualize Rho GTPases reveal how a protein called RhoGDI regulates the activity of these 'molecular switches' at the plasma membrane.
Two new unicellular organisms reveal that coordinated contractions of groups of cells using actomyosin predated animal multicellularity during evolution.