Browse our latest research

Page 652 of 1,752
    1. Cell Biology

    Cortical microtubule pulling forces contribute to the union of the parental genomes in the Caenorhabditis elegans zygote

    Griselda Velez-Aguilera, Batool Ossareh-Nazari ... Lionel Pintard
    Cortical microtubule pulling forces influence nuclear envelope breakdown, while nuclear envelope remodeling, particularly lamina depolymerization, impacts mitotic spindle length during mitosis.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Effect of cancer on outcome of COVID-19 patients: a systematic review and meta-analysis of studies of unvaccinated patients

    Giulia Di Felice, Giovanni Visci ... Paolo Boffetta
    A twofold increased risk of adverse outcomes (mortality, ICU admission, and severity of COVID-19) has been demonstrated in unvaccinated COVID-19 patients with cancer compared to COVID-19 patients without cancer.
    1. Ecology
    2. Physics of Living Systems

    Particle foraging strategies promote microbial diversity in marine environments

    Ali Ebrahimi, Akshit Goyal, Otto X Cordero
    An ecological trade-off between growth and death enables microbes with different dispersal strategies to coexist on particulate matter in the oceans.
    1. Medicine

    Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors

    Alexis Ruiz, Sofia Benucci ... Francesco Zorzato
    Physiological and biochemical studies show that the treatment of a transgenic mouse model carrying recessive Ryr1 mutations with a combination of class II histone deacetylase inhibitors and DNA methyl transferase inhibitors significantly improves skeletal muscle function.
    1. Neuroscience

    Associative learning drives longitudinally graded presynaptic plasticity of neurotransmitter release along axonal compartments

    Aaron Stahl, Nathaniel C Noyes ... Seth M Tomchik
    Experience alters neurotransmitter release from different axonal compartments in different ways, allowing a set of neurons to coherently modulate behavior through diverse actions on multiple downstream circuits.
    1. Developmental Biology
    2. Neuroscience

    Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types

    Karthik Shekhar, Irene E Whitney ... Joshua R Sanes
    Single-cell transcriptomic analysis of developing retinal ganglion cells in mice suggests that their diversification into 45 discrete types occurs via the gradual restriction of multipotential precursors.
    1. Structural Biology and Molecular Biophysics

    STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells

    Vivek Krishnan, Sher Ali ... Scott Earley
    STIM1 regulates the contractility of blood vessels and blood pressure by organizing membrane contact sites and ion channel activity in vascular smooth muscle cells in a manner that is independent of its canonical function in store-operated Ca2+entry.
    1. Neuroscience

    A unifying mechanism governing inter-brain neural relationship during social interactions

    Wujie Zhang, Maimon C Rose, Michael M Yartsev
    Experiments and modeling suggest that a mechanism involving positive and negative feedback can explain the relationship between the neural activity of socially interacting bats.
    1. Cell Biology
    2. Medicine

    Pericyte-mediated constriction of renal capillaries evokes no-reflow and kidney injury following ischaemia

    Felipe Freitas, David Attwell
    Renal capillary pericytes are a novel therapeutic target for reducing sustained reduction in renal blood flow ('no-reflow') after kidney ischaemia.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study

    Laurence J Howe, Ben Brumpton ... Neil M Davies
    Genetic data from siblings provides strong evidence that taller height increases the risk of cancers but lowers the risk of coronary disease.