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Computer simulations show how low-intensity illumination can be used to terminate cardiac arrhythmias.

A combination of X-ray crystallography, NMR, and mass spectrometry has revealed how diverse small-molecule inhibitors bind Bruton’s tyrosine kinase and alter the conformation of this enzyme.

Osteocalcin is a bone matrix protein that acts like a hormone when it reaches the blood, and has different effects in mice and humans.

Increasing validity should be a priority when deciding which preclinical experiments to replicate and when performing replications.

Atomic structures of mitochondrial enzyme complexes in plants are shedding light on their multiple functions.

A study of more than 75,000 grant proposals to the European Union indicates that the outcomes of the peer review process remain stable in response to changes in the way that peer review is organized.

Job insecurity is putting stress on early-career researchers in Australia, compromising their career development and potentially reducing the quality of research.

A simulation study demonstrates a better method for separating genetic effects from environmental effects in genome-wide association studies, but there is still some way to go before this becomes a "solved" problem.

During sleep, the brain experiences large fluctuations in blood volume and altered coupling between neural and vascular signals.

HOAP is a telomere-binding protein that has a conserved role in Drosophila, but it also needs to evolve quickly to restrict telomeric retrotransposons.