Highlights

  • Ribbon formation in hair cells

    Live imaging reveals role of microtubule networks in formation of ribbon synapses in zebrafish hair cells.

    Saman Hussain, Katherine Pinter ... Katie S Kindt
    Reviewed Preprint Updated
  • Genetics and structural color

    Structural color in a Flavobacterium can be changed by a mutation to a gene that is involved in polysaccharide metabolism.

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Reviewed Preprint Updated
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Convincing
    1. Immunology and Inflammation

    Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism

    Wesley H Godfrey, Judy J Lee ... Michael D Kornberg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Occupancy of the HbYX hydrophobic pocket is sufficient to induce gate opening in the archaeal 20S proteasomes

    Janelle JY Chuah, Madalena R Daugherty, David M Smith
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease
    2. Cancer Biology

    The lnc-FANCI-2 intrinsically restricts RAS signaling in HPV16-infected cervical cancer

    Haibin Liu, Lulu Yu ... Zhi-Ming Zheng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    The flexible stalk domain of sTREM2 modulates its interactions with brain-based phospholipids

    David Saeb, Emma E Lietzke ... Kayla G Sprenger
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Immunology and Inflammation

    Xcr1+ type 1 conventional dendritic cells are essential mediators for atherosclerosis progression

    Tianhan Li, Liaoxun Lu ... Lichen Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Odors drive feeding through gustatory receptor neurons in Drosophila

    Hong-ping Wei, Thomas Ka Chung Lam, Hokto Kazama
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Medicine

    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

    Fan Zhang, Yuan Wang ... Xianpeng Ge
    CHMP5 is crucial in preventing skeletal progenitor cell senescence and abnormal bone formation, and senolytic drugs represent potential therapeutic medicine for musculoskeletal abnormalities associated with a dysfunctional endolysosomal pathway.
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

    M Reza Bahranifard, Jessica Chan ... C Ross Ethier
    Magnetically steered mesenchymal stem cells significantly lowered intraocular pressure for 9 months in mice, motivating the translation of this technology for the treatment of glaucoma.