Highlights

Latest research

    1. Biochemistry and Chemical Biology

    Isolation of small extracellular vesicles from small volumes of blood plasma using size exclusion chromatography and density gradient ultracentrifugation

    Fang Kong, Megha Upadya ... Ming Dao
    The optimized protocol for isolating small extracellular vesicles from small blood volumes, confirmed by independent methods including cryo-electron microscopy, ensures superior purity and high yield for reliable biomarker detection.
    1. Neuroscience

    Involuntary feedback responses reflect a representation of partner actions

    Seth R Sullivan, John H Buggeln ... Joshua GA Cashaback
    High-level partner representations tune low-level visuomotor reflexes.
    1. Neuroscience

    Sexual dimorphism in sensorimotor transformation of optic flow

    Sarah Nicholas, Katja Sporar Klinge ... Karin Nordström
    Descending neurons that encode widefield motion vision in the fly have sexually dimorphic velocity tuning, while the wing beat amplitude, which these neurons presumably control, is monomorphic.
    1. Developmental Biology
    2. Immunology and Inflammation

    Mitochondrial metabolic remodeling drives innate immune activation in Drosophila hemocytes

    Daewon Lee, Ferdinand Koranteng ... Jiwon Shim
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease
    2. Neuroscience

    Enterovirus D68 2A protease causes nuclear pore complex dysfunction and independently contributes to motor neuron toxicity

    Katrina M Zinn, Mathew W McLaren ... Matthew J Elrick
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology

    Single-step in vitro ribosome reconstitution mediated by two GTPase factors, EngA and ObgE

    Aya Sato, Weng Yu Lai ... Yoshihiro Shimizu
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Medicine

    Magnesium isoglycyrrhizinate alleviates alcohol-associated liver disease through targeting HSD11B1

    Lu Xiao, Lu Li ... Jia Xiao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Simplified model of intrinsically bursting neurons

    Nikhil X Bhattasali, Lerrel Pinto, Grace W Lindsay
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Transcriptional responses to chronic oxidative stress require cholinergic activation of G-protein-coupled receptor signaling

    Kasturi Biswas, Caroline Moore ... Michael M Francis
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Epidemiology and Global Health

    A natural experiment in Kenya reveals durable immunosuppressive effects of early childhood malaria: a longitudinal cohort study

    Mercy S Safari, Timothy O Makori ... Charles J Sande
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid