All research categories

Highlights

  • Complex connections

    Optogenetics reveals that interactions between the basal ganglia and the pedunculopontine nucleus (PPN), a region that has a central role in motor control, are more complex than previously thought.

    Michel Fallah, Kenea C Udobi ... Rebekah C Evans
    Research Article

  • The benefits of disorder

    The presence of an intrinsically disordered region in a transcription factor enhances both target binding and search efficiency.

    Wencheng Ji, Ori Hachmo ... Ariel Amir
    Reviewed Preprint Updated

  • Genetic parallels

    Multiple genetic analyses reveal surprising parallels between biomineralization in stony corals and certain sponges.

    Oliver Voigt, Magdalena V Wilde ... Gert Wörheide
    Research Article

Latest research

    1. Physics of Living Systems

    Theory of active self-organization of dense nematic structures in the actin cytoskeleton

    Waleed Mirza, Marco De Corato ... Marino Arroyo
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    BetaII-Spectrin Gaps and Patches Emerge from the Patterned Assembly of the Actin/Spectrin Membrane Skeleton in Human Motor Neuron Axons

    Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel ... Nicolás Unsain
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    The electrogenicity of the Na+/K+-ATPase poses challenges for computation in highly active spiking cells

    Liz Weerdmeester, Jan-Hendrik Schleimer, Susanne Schreiber
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Evolutionary Biology

    Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies

    Kai S Shimagaki, Rebecca M Lynch, John P Barton
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response

    CJ San Felipe, Jyoti Batra ... James S Fraser
    Lipid binding stabilizes the SARS-CoV-2 Orf9b homodimer, slowing its conversion to the Tom70-binding monomeric form and modulating interferon suppression.
    1. Cancer Biology
    2. Medicine

    Monitoring circulating cell-free HPV DNA in metastatic or recurrent cervical cancer: clinical significance and treatment implications

    Zhuomin Yin, Tao Feng ... Hanmei Lou
    HPV cfDNA is a highly effective tumor marker for monitoring disease progression and treatment response in HPV-positive cervical cancer, offering valuable insights for guiding clinical decisions in precision medicine.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

    Chen Xie, Sven Künzel, Diethard Tautz
    Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.
    1. Cell Biology
    2. Genetics and Genomics

    Impact of maximal overexpression of a non-toxic protein on yeast cell physiology

    Yuri Fujita, Shotaro Namba ... Hisao Moriya
    A neutrality index identifies mox-YG as a minimally cytotoxic protein, enabling ultra-high expression and uncovering key physiological consequences of protein burden.
    1. Neuroscience

    A novel mouse model for LAMA2-related muscular dystrophy with analysis of molecular pathogenesis and clinical phenotype

    Dandan Tan, Yidan Liu ... Hui Xiong
    Analysis of phenotype and molecular pathogenesis in a new LAMA2-related muscular dystrophy mouse model.
    1. Structural Biology and Molecular Biophysics

    DIRseq: a method for predicting drug-interacting residues of intrinsically disordered proteins from sequences

    Matthew MacAinsh, Sanbo Qin, Huan-Xiang Zhou
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
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Magazine

    1. Developmental Biology

    Morphogenesis: Regulating closure of the neural tube in humans

    Leon Qarawani, Jacob H Hanna

  2. Episode 100: September 2025

    1. Neuroscience

    Numerical Cognition: Is ‘number sense’ a sense?

    Toshiya Matsushima
    1. Neuroscience

    Dorsal Vagal Complex: A cell atlas to guide research into appetite control

    Greta Lommi, Thomas A Lutz

  5. Point of View: How the Global South is reshaping scholarly communication

    Humberto Debat, Izuchukwu Azuka Okafor ... Carolina Santacruz-Perez
    1. Neuroscience

    Connectomes: The wiring diagram of an entire animal

    Alex M Winsor, Paul S Katz
    1. Plant Biology

    Equity, Diversity and Inclusion: Making conferences in the plant sciences more inclusive through community recommendations

    Marcia Puig-Lluch, Mary Williams ... Patricia Baldrich
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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