Highlights

Latest research

    1. Cell Biology

    Transdifferentiation of fibroblasts into muscle cells to constitute cultured meat with tunable intramuscular fat deposition

    Tongtong Ma, Ruimin Ren ... Heng Wang
    Efficient myogenic and lipogenic transdifferentiation of chicken fibroblasts in 3D culture produces meat with precisely controlled levels of intramuscular fat and extracellular matrix.
    1. Immunology and Inflammation

    Inhibition of miR-199b-5p reduces pathological alterations in osteoarthritis by potentially targeting Fzd6 and Gcnt2

    Tong Feng, Qi Zhang ... Qiao-Feng Wu
    Serum exosomal sequencing combined with cell and animal experiments indicate that miRNA-199b-5p is a novel miRNA associated with osteoarthritis (OA) and can modulate the onset and progression of the disease.
    1. Neuroscience

    A fear conditioned cue orchestrates a suite of behaviors in rats

    Amanda Chu, Nicholas T Gordon ... Michael A McDannald
    1. Microbiology and Infectious Disease

    Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics

    Tomoko Kubori, Kohei Arasaki ... Hiroki Nagai
    Interplay between multiple Legionella pneumophila effector proteins lead to spatial and temporal regulation of the host Rab10 localization to the bacterial vacuole by controlling noncanonical ubiquitin modifications.
    1. Cell Biology

    Clearance of protein aggregates during cell division

    Shoukang Du, Yuhan Wang ... Ting Gang Chew
    1. Neuroscience

    A ventral hippocampal-lateral septum pathway regulates social novelty preference

    Maha Rashid, Sarah Thomas ... Malavika Murugan
    1. Cell Biology
    2. Developmental Biology

    Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary

    Dilara N. Anbarci, Jennifer McKey ... Blanche Capel
    1. Developmental Biology
    2. Medicine

    The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

    Rion Brattig Correia, Joana M. Almeida ... Paulo Navarro-Costa