Highlights

Latest research

    1. Neuroscience

    The generalized Hierarchical Gaussian Filter

    Lilian Aline Weber, Peter Thestrup Waade ... Christoph Mathys
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Nuclear export governs TDP-43 phase transitions and cytoplasmic aggregation

    Natalie Chin, Qi Zhang ... Yihong Ye
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Immunology and Inflammation

    Adaptor protein supersaturation drives innate immune signaling and cell fate

    Alejandro Rodriguez Gama, Tayla Miller ... Randal Halfmann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cancer Biology

    Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids

    Yanping Li, Xiaoxin Xie ... Qionghua Zhu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Autosomal Allelic Inactivation: Variable Replication and Dosage Sensitivity

    Michael B Heskett, Athanasios E Vouzas ... Mathew J Thayer
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Constraints on the G1/S transition pathway may favor selection of multicellularity as a passenger phenotype

    Tom Louis Ducrocq, Damien Laporte, Bertrand Daignan-Fornier
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Genetics and Genomics

    JAX Animal Behavior System (JABS), a genetics-informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    The JAX Animal Behavior System integrates standardized hardware, machine learning methods, and annotated datasets to enable reproducible behavioral phenotyping and genetic analysis across diverse mouse strains.
    1. Neuroscience

    Resolving synaptic events using subsynaptically targeted GCaMP8 variants

    Jiawen Chen, Junhao Lin ... Dion K Dickman
    New synaptically targeted GCaMP8 sensors and analysis tools capture calcium dynamics with the speed and sensitivity previously achievable only through electrophysiology and chemical dyes.
    1. Computational and Systems Biology
    2. Ecology

    Agent-based modeling reveals how bats navigate dense group emergences

    Omer Mazar, Yossi Yovel
    Acoustic jamming during bat emergence is weaker than expected because signal redundancy, echo integration, and simple movement rules enable robust navigation, as demonstrated by an agent‑based sensory-motor model.
    1. Neuroscience

    Visual experience shapes functional connectivity between occipital and non-visual networks

    Mengyu Tian, Xiang Xiao ... Marina Bedny
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing