Highlights

  • Re-evolving traits

    Hybridization chain reaction and confocal imaging reveal latent ocelli gene regulatory network expression in ant workers, with a role in partial re-evolution of caste-specific traits.

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Research Article
  • Body size and urban survival

    A global study of 30,000 species reveals how body size affects whether wildlife thrives or struggles in cities.

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Research Article
  • T-cells target TB-infected cells

    Complementary human in vitro systems suggest a non-classical T-cell pathway contributing to immunity against Mycobacterium tuberculosis infection

    Matthew Milton, Sahar H Farag ... Salah Mansour
    Reviewed Preprint Updated
  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

Latest research

    1. Genetics and Genomics

    AGES for Ageing: Evaluating the auxin-inducible gene expression system for use in Drosophila ageing studies

    Taylor McGilvary, Kriti Gupta ... Nathan Woodling
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    Supervised Domain Adaptation Mitigates Cross-Ethnicity Prediction Error in Neuroimaging-Based Cognitive Prediction

    Farzane Lal Khakpoor, William van der Vliet ... Narun Pat
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    WNK-SPAK/OSR1 signaling pathway facilitates ictal activity via reduced neuronal chloride extrusion rate

    Volodymyr I Dzhala, Fu Hung Shiu ... Kevin J Staley
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Selective loss of Nkx2.1-lineage neurons in the lateral septum alters the balance between novelty seeking and threat avoidance

    Miguel Turrero García, Diana N Tran ... Corey C Harwell
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Inhibition tunes prefrontal circuit dynamics to promote sociosexual behavior in female mice

    Elizabeth A Amadei, Pau Vilimelis Aceituno ... Benjamin F Grewe
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Fast-ripples are emergent properties of neuronal networks

    Laurent Sheybani, Yichen Qiu ... Matthew C Walker
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    The transcription factor BCL11A restores differentiation potential to aged oligodendrocyte progenitor cells

    Tanay Ghosh, Roey Baror ... Robin JM Franklin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Individual differences in fear memory expression engage distinct functional brain networks

    Barbara D Fontana, Jacob Hudock ... Justin W Kenney
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Nim1-related kinases regulate septin organization and cytokinesis by modulating Hof1 at the cell division site

    Bindu Bhojappa, Anubhav Dhar ... Saravanan Palani
    Septin-associated kinases functions in an adaptable regulatory network with overlapping functions to coordinate septin organization with actomyosin ring machinery to ensure robust cytokinesis in Saccharomyces cerevisiae.
    1. Cancer Biology

    Serum, cell-free, HPV-human DNA junction detection and HPV typing for predicting and monitoring cervical cancer recurrence

    Anne R Van Arsdale, Olga Meshcheryakova ... Jack Lenz
    HPV-human DNA junction detection in serum cell-free DNA unambiguously identifies tumor genetic-signatures of integrated viral DNA from HPV-induced cancers and could be useful for recurrence prediction and monitoring residual disease.