Highlights

Latest research

    1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure

    Ian S Prudhomme, Eric R Brooks ... Jennifer A Zallen
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Evolutionary Biology

    Design and experimental characterization of specificity-switching mutational paths of WW domains

    Ahmed Rehan, Eugenio Mauri ... Simona Cocco
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Challenges in replay detection by TDLM in post-encoding resting state

    Simon Kern, Juliane Nagel ... Gordon B Feld
    Detecting replay during longer time periods (e.g. resting state or sleep) with temporally delayed linear modeling (TDLM) requires biologically implausible event densities, and purely synthetic simulations substantially overestimate the method's sensitivity.
    1. Neuroscience

    The dominance of large-scale phase dynamics in human cortex, from delta to gamma

    David M Alexander, Laura Dugué
    The phase of cortical activity, measured in the gray matter, is organized at multiple spatial scales, with the largest scales explaining most variance in phase at a given temporal frequency.
    1. Cell Biology

    Specialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy

    Lori B Koch, Tiasha Ghosh ... Adèle L Marston
    A system to enrich yeast in metaphase of mitosis, meiosis I, or meiosis II reveals reduced spindle assembly checkpoint robustness in meiosis I and distinct kinetochore composition and phosphorylation states.
    1. Developmental Biology

    Membrane rupture and independent extension of sister membranes drive cytokinesis in C. elegans embryos

    Jingjing Liang, Tingrui Huang ... Mei Ding
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Cell Biology
    2. Developmental Biology

    Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension

    Hwa-seon Seo, Deli Yu ... Jianbo Wang
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    The Dual Molecular Identity of Vestibular Kinocilia: Bridging Structural and Functional Traits of Primary and Motile Cilia

    Zhenhang Xu, Amirrasoul Tavakoli ... David Z He
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling