Highlights

  • Re-evolving traits

    Hybridization chain reaction and confocal imaging reveal latent ocelli gene regulatory network expression in ant workers, with a role in partial re-evolution of caste-specific traits.

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Research Article

  • Body size and urban survival

    A global study of 30,000 species reveals how body size affects whether wildlife thrives or struggles in cities.

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Research Article

  • T-cells target TB-infected cells

    Complementary human in vitro systems suggest a non-classical T-cell pathway contributing to immunity against Mycobacterium tuberculosis infection

    Matthew Milton, Sahar H Farag ... Salah Mansour
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Neuroscience

    GPCR-mediated regulation of glial TNF production

    Zahra Abbasi, Shirin Sadighparvar ... David Stellwagen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Inadequate
    1. Neuroscience

    Crossmodal representations in the auditory cortex of deaf and hearing individuals

    Barbara Manini, Konstantin Grin ... Velia Cardin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression

    Dual regulation of chemical stress-induced DDI2/3 expression by a transcription factor Fzf1 and nucleosome in Saccharomyces cerevisiae

    Ying Du, Aiyang Lin ... Wei Xiao
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Retinotopic coding organizes the interaction between internally and externally oriented brain networks

    Adam Steel, Peter A Angeli, Caroline E Robertson
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Biochemistry and Chemical Biology

    A simplified and highly efficient cell-free protein synthesis system for prokaryotes

    Xianshengjie Lang, Changbin Zhang ... Wenfei Li
    A streamlined seven-component cell-free expression platform simplifies reaction design while maintaining high productivity and enabling robust synthesis of challenging proteins for diverse applications.
    1. Ecology

    Small mammalian herbivores at moderate densities facilitate livestock growth by improving vegetation composition in grasslands

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    At moderate densities, small mammalian herbivores can enhance livestock weight gains by suppressing toxic plants and improving both the abundance and nutritional quality of palatable forage in rangelands.
    1. Cell Biology
    2. Neuroscience

    BetaII-spectrin gaps and patches emerge from the patterned assembly of the actin/spectrin membrane skeleton in human motor neuron axons

    Nahir Guadalupe Gazal, Maria Jose Castellanos-Montiel ... Nicolás Unsain
    An actin-nucleation-dependent assembly of the axonal membrane skeleton reveals that βII-spectrin gap-and-patch patterns in human motor neurons represent an intermediate stage of cytoskeletal maturation.
    1. Neuroscience

    Cortical layer 6b mediates state-dependent changes in brain activity and effects of orexin on waking and sleep

    Elise J Meijer, Marissa Mueller ... Zoltan Molnar
    Layer 6b neurons shape state-dependent brain rhythms and responses to orexin, revealing an underappreciated cortical mechanism that may help explain disrupted sleep-wake regulation in neurodevelopmental and psychiatric disorders more broadly.
    1. Cell Biology

    Centrosome migration and apical membrane formation during epithelial polarization in MDCK cysts

    Po-Kai Wang, Keng-Hui Lin, Tang K Tang
    Single-cell observations refute the expectation that centrosome positioning is critical for epithelial cell polarization while showing that proper positioning enhances polarization efficiency.
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Magazine

  1. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
    1. Plant Biology

    Mixotrophy: An updated view of glucose pathways in cyanobacteria

    José Manuel García-Fernández
  6. Mountain gorilla

    Episode 104: July 2026

    1. Cell Biology
    2. Developmental Biology

    Organ Development: Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Physiology
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  18. Stem Cells and Regenerative Medicine
  19. Structural Biology and Molecular Biophysics
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