Highlights

  • Context-dependent behavior

    A region of the brain called the retrosplenial cortex has an important role in integrating contextual information and sensory stimuli in mice.

    Pol Bech, Robin F Dard ... Carl CH Petersen
    Reviewed Preprint Updated
  • Seeing movement

    Inhibitory feedback from GABAergic interneurons C2 and C3 is tied to neural computation of moving visual stimuli in Drosophila.

    Miriam Henning, Madhura D Ketkar ... Marion Silies
    Research Article
  • Testing the blood-brain barrier

    pdgfrb knockout zebrafish, which lack mural cells in their neurovasculature, retain restrictive permeability of the blood-brain barrier during developmental stages.

    Oguzhan F Baltaci, Andrea Usseglio Gaudi ... Benjamin M Hogan
    Research Article
  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial
  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
  • How to respond to peer reviewers

    Responding to peer reviews is a crucial part of publishing, but early-career researchers are rarely taught about it.

    Eric Kalkhoven, Manon Kluijtmans
    Feature Article

Latest research

    1. Neuroscience

    Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity

    Anne Sustar, Chengjie Qiu ... John C Tuthill
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

    Chelsey C Damphousse, Olivia L Calvin, A David Redish
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Human decision-makers terminate evidence accumulation using flexible decision rules

    Ishan Kalburge, Alice Dallstream ... Joshua I Gold
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella-containing vacuole

    Adriana Steinbach, Chetan Mokkapati ... Shaeri Mukherjee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology

    Nuclear CK1δ as a critical determinant of PER:CRY complex dynamics and circadian period

    Fidel Emmanuel Serrano, Daniela Marzoll ... Michael Brunner
    Repressive PER2:CRY1:CK1δ complexes assembling in the cytosol enter the nucleus, where PER2 hyperphosphorylation eventually disrupts the complex, causing PER2 to relocalize to the cytoplasm, allowing nuclear accumulation of CRY1.
    1. Neuroscience

    Exposure to false cardiac feedback alters pain perception and anticipatory cardiac frequency

    Eleonora Parrotta, Patric Bach ... Francesca Ferri
    Interoceptive predictions can bias both the subjective experience of pain and physiological preparation.
    1. Neuroscience
    2. Ecology

    The neuronal clock network in the polar key species Antarctic krill (Euphausia superba)

    Lukas Hüppe, Nils Reinhard ... Charlotte Helfrich-Förster
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Perceiving animacy in ‘identical’ images

    Tal Boger, Chaz Firestone
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Ramping-up hippocampal ripples and their neocortical coupling support human visual short-term memory

    Jing Liu, Xianhui He ... Ying Cai
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete