Highlights

  • Closing the neural tube

    High-throughput arrayed CRISPR interference screening of organoid models gives insight into genetic regulators of neural tube closure in humans.

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Research Article

  • Mechanics of oncogenesis

    Integrative mechanobiological approaches provide insight into the biophysics of tissue-specific tumor growth.

    Amrapali Datta, Phanindra Dewan ... Medhavi Vishwakarma
    Research Article

  • Pikas power yak pastures

    Plateau pikas play a role in enhancing weight gains in yaks, by suppressing toxic plants and improving the availability and quality of palatable forage.

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    Reviewed Preprint Updated

  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial

  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife

  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article
We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat of rejection.

Patrick Allard, UCLA and eLife author

Researchers explain why they published in eLife

Latest research

    1. Genetics and Genomics
    2. Evolutionary Biology

    Genome-wide architecture of prolonged starvation adaptation in experimentally evolved Drosophila and comparative enrichment in human orthologs

    Gaurav Yadav, Prachi Mishra ... Dau Dayal Aggarwal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Ecology

    Eco-genomic analysis uncovers precision-conservation targets for the western Pacific’s southernmost salmonid

    Yi-Chien Lee, Zong-Yu Shen ... Sheng-Feng Shen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    PRRT2 as an auxiliary regulator of Nav channel slow inactivation

    Bin Lu, Qi-Wu Xu ... Zhi-Qi Xiong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Neural computations in the foveal and peripheral visual fields during active search

    Jie Zhang, Xiaocang Zhu ... Huihui Zhou
    Foveal attentional processing coordinates with peripheral attention to dynamically shape global attention allocation and fixation behavior during active vision.
    1. Physics of Living Systems

    Viral commitment to infection depends on host metabolism

    Anastasios Marantos, Kim Sneppen ... Namiko Mitarai
    Energy-limited bacterial cells reduce phage adsorption, particularly for weakly binding viruses, revealing host physiology as a key factor in viral commitment to infection.
    1. Genetics and Genomics
    2. Neuroscience

    The Drosophila IR20a Integrates L-arginine and Salt Signals via Distinct Subunit Assemblies

    Bo Wang, Guangnan Qu ... Yan Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Chromosomes and Gene Expression

    Genome-wide mapping of Cas9-induced sister chromatid exchange across single and over 200 genomic targets

    Peter Chovanec, Shiyang He, Yi Yin
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Prophase Chromosomes Relocalization to Nuclear Periphery in NPP-3/NUP205 Depletion Protects Genome Stability

    Ling Jiang, Yu Chung Tse, Karen Wing Yee Yuen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Evolutionary Biology

    Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci

    Michele Marconcini, Steeve Cruchet ... Richard Benton
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Identifying Novel Estrogenic Mitochondrial Targets in Hypothalamic Proopiomelanocortin Neurons by Chemoproteomics

    Jian Qiu, Martha A Bosch ... Martin J Kelly
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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Magazine

  1. Point of View: Scientific writing is not a murder mystery

    Charlotte A Dodson
    1. Neuroscience

    Visual Categorization: How monkeys carve up the visual world

    Binxu Wang
    1. Cell Biology

    Stress: How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Epidemiology and Global Health

    Malaria Prevention: Using mathematical models to optimise mosquito net distribution

    Carlos A Prete Jr
    1. Plant Biology

    Mixotrophy: An updated view of glucose pathways in cyanobacteria

    José Manuel García-Fernández
  6. Mountain gorilla

    Episode 104: July 2026

    1. Cell Biology
    2. Developmental Biology

    Organ Development: Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
  8. See more Magazine articles

Categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
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  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
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  11. Immunology and Inflammation
  12. Medicine
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