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    Clusters of synapses develop in the primary visual cortex in young mice before they open their eyes for the first time.

    Alexandra H. Leighton, Juliette E. Cheyne, Christian Lohmann
    Reviewed Preprint Updated

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    From July 1, the fee for Reviewed Preprints will increase from $2,000 to $2,500 to support sustainability of our publishing.

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  • Decoding spike signatures

    Nuclei cells in the cerebellum produce distinct spike signatures for ataxia, dystonia, and tremor in mouse models.

    Meike E. van der Heijden, Amanda M. Brown ... Roy V. Sillitoe
    Reviewed Preprint Updated

Latest research

    1. Neuroscience

    A fear conditioned cue orchestrates a suite of behaviors in rats

    Amanda Chu, Nicholas T Gordon ... Michael A McDannald
    Comprehensive behavioral ethograms reveal a fear conditioned cue to elicit a temporally organized suite of behaviors spanning freezing, locomotion, rearing, and jumping.
    1. Cancer Biology
    2. Cell Biology

    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

    Savvas Nikolaou, Amelie Juin ... Laura M Machesky
    Macropinocytosis of the signalling receptor LPAR1, by an actin and CYRI-B-dependent mechanism, impacts on progression and spread of pancreatic cancer in a mouse model.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)

    Fayang Zhou, Yuanyuan Zhang ... Qi Hu
    1. Cell Biology

    A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture

    Rachel Pudlowski, Lingyi Xu ... Jennifer T. Wang
    1. Neuroscience

    Chronic activation of a negative engram induces behavioral and cellular abnormalities

    Alexandra L. Jellinger, Rebecca L. Suthard ... Steve Ramirez
    1. Stem Cells and Regenerative Medicine

    PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification

    José Antonio Valer, Alexandre Deber ... Francesc Ventura
    1. Genetics and Genomics

    SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

    Kira Breunig, Xiufen Lei ... Luiz O. F. Penalva
    1. Neuroscience

    Nutritional state-dependent modulation of Insulin-Producing Cells in Drosophila

    Rituja S. Bisen, Fathima Mukthar Iqbal ... Jan M. Ache
    1. Neuroscience

    Neural Trajectories of Conceptually Related Events

    Matthew Schafer, Philip Kamilar-Britt ... Daniela Schiller
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal Changes in Netrin/Dscam1 Signaling Dictate Axonal Projection Direction in Drosophila Small Ventral Lateral Clock Neurons

    Jingjing Liu, Yuedong Wang ... Yao Tian
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Magazine

    1. Cell Biology
    2. Physics of Living Systems

    Cell Migration: Pump up the volume

    Qin Ni, Sean X Sun
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Viral Variants: How mutations affect function

    Thomas Kuhlman

  3. Episode 93: June 2023

    1. Computational and Systems Biology

    Protein Kinases: Redox takes control

    Iván Plaza-Menacho
    1. Neuroscience

    Behavior: Prompting social investigation

    Emma Keppler, Susanna Molas
    1. Neuroscience

    Vision: Paying attention

    Christian H Poth
    1. Evolutionary Biology

    Synthetic Biology: Shining a light on Ohno’s dilemma

    Isabella Tomanek
  8. See more Magazine articles

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