Highlights

Latest research

    1. Cell Biology
    2. Neuroscience

    Age-dependent H3K9 trimethylation by dSetdb1 impairs mitochondrial UPR leading to degeneration of olfactory neurons and loss of olfactory function in Drosophila

    Francisco Muñoz-Carvajal, Nicole Sanhueza ... Felipe A Court
    Age-related epigenetic regulation of mitochondrial stress responses drives neuronal degeneration and sensory decline, highlighting mitochondrial resilience as a potential target to preserve brain function during aging.
    1. Epidemiology and Global Health

    Prediction of SARS-CoV-2 transmission dynamics based on population-level cycle threshold values: An epidemic transmission and machine learning modeling study

    Afraz Arif Khan, Hind Sbihi ... Catherine A Hogan
    Modeling approaches demonstrate utility for incidence and reproductive number prediction and have potential to complement traditional surveillance in real time to guide public health interventions.
    1. Neuroscience

    A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function

    Anna Vasilevskaya, Georg B Keller
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Chromosomes and Gene Expression

    Single Domain Antibody Inhibitors Target the Coiled Coil Arms of the Bacillus subtilis SMC complex

    Ophélie Gosselin, Michael Taschner ... Stephan Gruber
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Physics of Living Systems

    Universal length fluctuations of actin structures found in cells

    Aldric Rosario, Shane G McInally ... Jane Kondev
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Genetics and Genomics

    Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenyan Women Diagnosed with Breast Cancer

    Michael Kitoi, John Gitau ... Francis Makokha
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Probing the role of sequential sampling and integration in decisions about protracted, noiseless stimuli

    Hadiseh Hajimohammadi, Kieran S Mohr ... Simon P Kelly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Mettl5 coordinates protein production and degradation of PERIOD to regulate sleep in Drosophila

    Xiaoyu Wu, Xingzhuo Yang ... Juan Du
    The Mettl5/Trmt112 complex alters rRNA methylation, increasing PERIOD protein linking ribosome function, clock genes, and proteasome in sleep regulation in Drosophila.
    1. Neuroscience

    Neural representation of time across complementary reference frames

    Yangwen Xu, Nicola Sartorato ... Roberto Bottini
    Humans’ flexible temporal cognition, including mental time travel, arises from perspective-agnostic encoding of event sequences in the hippocampus and perspective-dependent retrieval and reconstruction in the posterior parietal cortex.
    1. Ecology
    2. Evolutionary Biology

    Adaptive variation in avian eggshell gas conductance and structure across elevational gradients?

    David Ocampo, Carlos Daniel Cadena ... Gustavo A Londoño
    In Neotropical birds, eggshells show that water vapor conductance declines with elevation, but structural responses vary across species, suggesting no single underlying mechanism and highlighting the need to further evaluate eggshell traits as determinants of elevational limits.