Highlights

  • Body size and urban survival

    A global study of 30,000 species reveals how body size affects whether wildlife thrives or struggles in cities.

    Corey T Callaghan, Diana E Bowler ... Thomas Merckx
    Research Article
  • Pikas power yak pastures

    Plateau pikas play a role in enhancing weight gains in yaks, by suppressing toxic plants and improving the availability and quality of palatable forage.

    Zhiwei Zhong, Bingbo Ni ... Zhibin Zhang
    Reviewed Preprint Updated
  • Re-evolving traits

    Hybridization chain reaction and confocal imaging reveal latent ocelli gene regulatory network expression in ant workers, with a role in partial re-evolution of caste-specific traits.

    Angelly Vasquez-Correa, Johanna Arnet ... Ehab Abouheif
    Research Article
  • Publish-review-curate at eLife

    eLife is rethinking how research is reviewed and published.

    Timothy E Behrens, Yamini Dalal, Diane M Harper
    Editorial
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Science under threat

    How should the scientific community respond to ideological attacks on science?

    Humberto J Debat
    Feature Article

Latest research

    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

    Rayne R Lim, Emily Zhao ... Jennifer R Chao
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Chromosomes and Gene Expression

    Volatile diacetyl triggers rapid fmo-2 expression through DHAP-glycerol shunt induction

    Marco Giorda, Anamitra Sen, Martin S Denzel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Mapping abstraction and metacognition onto distinct transdiagnostic symptom profiles

    Taiki Oka, Yoshihiko Kunisato ... Aurelio Cortese
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Immunology and Inflammation

    CD56dimCD16dim NK cells are the dominant effector cells against HIV-infected primary T-cells

    William Howell, Courtney Branch ... Edward Barker
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacterial and viral gut microbiome alterations characterize microbiome-immune-pathophysiology axes in sickle cell disease

    Zachary N Flamholz, Jennifer De Los Santos ... Libusha Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A high-throughput assay for the measurement of Ca2+-oscillations and insulin release from uniformly sized β-cell spheroids

    Stijn Robben, Patricia Davidson ... Thomas Voets
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Bifunctional Architecture Enables Substrate Catalysis and Channeling in Paracoccus TMAO Demethylase

    Trung Thach, KanagaVijayan Dhanabalan ... Ramaswamy Subramanian
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Incomplete
    1. Neuroscience

    Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation

    Zhiyi Chen, Zhilin Ren ... Tingyong Feng
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Distinct sensorimotor encoding in tuft dendrites and somata associated with action, correction, and learning

    Jackson Scheib, Zachary L Newman ... Aaron Kerlin
    The tuft dendrites of neurons in the premotor cortex are uniquely selective for corrective actions, suggesting a specialized role in motor control and motor learning.
    1. Cell Biology

    Cardiolipin deficiency disrupts electron transport chain and drives steatohepatitis

    Marisa J Brothwell, Guoshen Cao ... Katsuhiko Funai
    Metabolic dysfunction-associated steatotic liver disease is associated with reduced mitochondrial cardiolipin concentration in mice and humans, and cardiolipin deficiency was sufficient to drive steatosis and fibrosis in the liver.