Highlights

  • Secrets of metamorphosis

    Interactions between different G-protein signalling pathways ensure that metamorphosis begins in a timely manner in the chordate Ciona.

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Research Article
  • Tapeworm larvae and epilepsy

    Amino acids released by larvae of the tapeworm Taenia solium disrupt glutamatergic signalling, which could explain the epileptic seizures caused by these parasites.

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Research Article
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Structural Biology and Molecular Biophysics

    Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy

    Giulia Arecchi, Marica Dente ... Chiara Tesi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin

    Jessica Mella, Regan Volk ... Abigail Buchwalter
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Gene expression variation across genetically identical individuals predicts reproductive traits

    Amy K Webster, John H Willis ... Patrick C Phillips
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Thrifty wide-context models of B cell receptor somatic hypermutation

    Kevin Sung, Mackenzie M Johnson ... Frederick A Matsen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Progressive neural engagement within the IFG-pMTG circuit as gesture and speech entropy and MI advances

    Wanying Zhao, Zhouyi Li ... Yi Du
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Physics of Living Systems

    Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

    Charuhansini Tvishamayi, Farhan Ali ... Shashi Thutupalli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    Dimerization and dynamics of angiotensin-I converting enzyme revealed by cryo-EM and MD simulations

    Jordan M Mancl, Xiaoyang Wu ... Wei-Jen Tang
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Striatal Crosstalk Between Dopamine and Serotonin Systems

    Yu Liu, Juan Enriquez Traba, Christian Lüscher
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    SoxB1 family members inhibit Wnt signaling to promote maturation and deposition of stable neuromasts by the zebrafish Posterior Lateral Line primordium

    Greg Palardy, Kyeong-won Yoo ... Ajay B Chitnis
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path

    Masataka Yamauchi, Giovanni B Brandani ... Shoji Takada
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing