Highlights

  • Secrets of metamorphosis

    Interactions between different G-protein signalling pathways ensure that metamorphosis begins in a timely manner in the chordate Ciona.

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Research Article
  • Tapeworm larvae and epilepsy

    Amino acids released by larvae of the tapeworm Taenia solium disrupt glutamatergic signalling, which could explain the epileptic seizures caused by these parasites.

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Research Article
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Real-time transcriptomic profiling in distinct experimental conditions

    Tamer Butto, Stefan Pastore ... Susanne Gerber
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    C. elegans food choice exhibits effort discounting-like behavior

    Jonathan RM Millet, Serge Faumont ... Shawn R Lockery
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Ecology

    Developmental constraints mediate the summer solstice reversal of climate effects on European beech bud set

    Dominic Rebindaine, Thomas W Crowther ... Constantin M Zohner
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Age and Learning Shapes Sound Representations in Auditory Cortex During Adolescence

    Benedikt Praegel, Feng Chen ... Adi Mizrahi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Rapid rebalancing of co-tuned ensemble activity in the auditory cortex

    HiJee Kang, Travis A Babola, Patrick O Kanold
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics

    Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

    Nicholas Tolman, Taibo Li ... Simon WM John
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

    Robert N Rainey, Sam D Houman ... Neil Segil
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability

    Joshua D Garcia, Chenyu Wang ... Kevin J Bender
    NaV1.2 and NaV1.6 have unique functional roles in neocortical pyramidal cells, regulating dendritic and axonal excitability, respectively.