All research categories

Highlights

  • Measures of consciousness

    The methods used to assess whether stimuli are ‘seen’ (conscious) or ‘unseen’ (unconscious) have an impact of neural measures of consciousness. Image: Matthew Willis (CC BY 4.0).

    Johannes J Fahrenfort, Philippa A Johnson ... Simon van Gaal
    Reviewed Preprint Updated

  • Exploring vascular disease

    Interactions between fibroblast cells and smooth muscle cells have a central role in the development of pulmonary hypertension.

    Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
    Research Article

  • Looking at lens development

    A study in mice reveals key interactions between the proteins involved in fibroblast growth factor (FGF) signaling and how they contribute to distinct stages of eye lens development.

    Qian Wang, Hongge Li ... Xin Zhang
    Reviewed Preprint Updated

Latest research

    1. Cell Biology
    2. Developmental Biology

    Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

    Pavan K Nayak, Arul Subramanian, Thomas F Schilling
    Muscle contraction forces shape tenocyte gene expression, with sequencing and spatial analyses revealing unique force-dependent gene regulation patterns, suggesting tenocytes fine-tune tendon matrix in response to varied mechanical cues.
    1. Genetics and Genomics
    2. Medicine

    EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

    Lianlei Wang, Xinyu Yang ... Nan Wu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9

    Helen B Belato, Alexa L Knight ... George P Lisi
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Neural substrates of cold nociception in Drosophila larva

    Atit A Patel, Albert Cardona, Daniel N Cox
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani

    Supratim Pradhan, Dhruba Dhar ... Budhaditya Mukherjee
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    A multiplex of connectome trajectories enables several connectivity patterns in parallel

    Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Tumor Cell Spatial Organization Directs EGFR/RAS/RAF Pathway Primary Therapy Resistance through YAP Signaling

    Rachel Nakagawa, Andrew Beardsley ... Andrei Goga
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo

    Cora Demler, John C Lawlor ... Natasza A Kurpios
    A novel midline barrier is discovered in the developing gut, highlighting its dynamics and function, with broad implications for patterning mechanisms, extracellular matrix significance, and laterality disorders.
    1. Immunology and Inflammation
    2. Neuroscience

    Microglia aging in the hippocampus advances through intermediate states that drive activation and cognitive decline

    Jeremy M Shea, Saul A Villeda
    During aging, microglia progress through intermediate cellular states, including stress response and translation upregulation states, that modulate subsequent activation and impact cognitive decline.
    1. Neuroscience

    A toolbox for ablating excitatory and inhibitory synapses

    Aida Bareghamyan, Changfeng Deng ... Don B Arnold
    Novel genetically encoded tools PFE3, paGFE3, and chGFE3 can be used to reversibly ablate excitatory synapses constitutively, and inhibitory synapses in a light- or chemically dependent manner.
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Magazine

  1. Image of the female leafhopper Macrosteles quadrilineatus

    Episode 98: April 2025

    1. Neuroscience

    Cognition: When working memory works for our goals

    Jacob A Miller
    1. Cancer Biology
    2. Cell Biology

    Breast Cancer: How cell crowding causes cancer cells to spread

    Rui Hua, Jean X Jiang
    1. Neuroscience

    Pain: Revisiting the role of Substance P and CGRPα

    Weihua Cai, Arkady Khoutorsky
    1. Genetics and Genomics
    2. Neuroscience

    Neuronal Signaling: Cell-specific tools for understanding behavior

    Brandon L Holder, Stephane Dissel
    1. Cell Biology
    2. Medicine

    Pulmonary Hypertension: When cell teamwork turns toxic

    Wadih EI Khoury, Stephen Y Chan

  7. Equity, Diversity and Inclusion: Improving gender equity in academia depends on the workplace environment

    Sreetama Bhadra, Gabriella Damasceno ... Alexandra Weyrich
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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