Latest research

1. 1. Cell Biology

   Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca²⁺ signalling to control glucose-dependent insulin secretion

   Dillon Jevon et al.

   The essential role of focal adhesion kinase in locally regulating insulin secretion and calcium responses in pancreatic beta cells is identified through the use of the pancreatic slice technique.
2. 1. Neuroscience

   Modified viral-genetic mapping reveals local and global connectivity relationships of ventral tegmental area dopamine cells

   Kevin Beier
3. 1. Genetics and Genomics
   2. Neuroscience

   Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3

   Junhao Li et al.
4. 1. Computational and Systems Biology
   2. Epidemiology and Global Health

   Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

   Bitya Raphael-Mizrahi et al.
5. 1. Neuroscience
   2. Stem Cells and Regenerative Medicine

   Chondroitin Sulfate Proteoglycan 4,6 sulfation regulates sympathetic nerve regeneration after myocardial infarction

   Matthew R Blake et al.
6. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Dcp2 C-terminal cis-binding elements control selective targeting of the decapping enzyme by forming distinct decapping complexes

   Feng He et al.
7. 1. Neuroscience

   Contractile force assessment methods for in vitro skeletal muscle tissues

   Camila Vesga-Castro et al.

   A standardized comparison of contractile force among in vitro muscle tissues across different platforms requires proper normalization with the contractile area and complementary morphological, maturation, and functional analysis to reduce variability and boost a new generation of engineered constructs.
8. 1. Structural Biology and Molecular Biophysics

   Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

   Maicon Landim-Vieira et al.

   Analytical techniques and computational models reveal novel post-translational modifications on β-myosin heavy chain in the human hearts and highlight their potential as therapeutic targets.
9. 1. Evolutionary Biology
   2. Genetics and Genomics

   Epistatic selection on a selfish Segregation Distorter supergene – drive, recombination, and genetic load

   Beatriz Navarro-Dominguez et al.

   African haplotypes of a meiotic drive supergene in Drosophila melanogaster called Segregation Distorter show signs of a recent selective sweep, reduced recombination, and increased genetic load.
10. 1. Neuroscience

    Human visual gamma for color stimuli

    Benjamin J Stauch et al.

    Colored surfaces induce gamma oscillations in human early visual cortex that are equally strong for red and green colors when L-M cone contrast is controlled for.