The impact of mitochondrial defects on sperm cells

Latest research

1. 1. Computational and Systems Biology

   A transfer-learning approach to predict antigen immunogenicity and T-cell receptor specificity

   Barbara Bravi, Andrea Di Gioacchino ... Rémi Monasson

   An interpretable machine learning approach can recapitulate the molecular features associated to immune protein-protein binding and leverage them for the prediction of immune response specificity.
2. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Synchronization of oscillatory growth prepares fungal hyphae for fusion

   Valentin Wernet, Marius Kriegler ... Reinhard Fischer

   Fungal hyphae constantly undergo signal oscillations, comparable to a cell 'monologue' until they meet another hypha with which they then coordinate signal oscillations and transit into a cell-to-cell dialogue.
3. 1. Cell Biology
   2. Microbiology and Infectious Disease

   A CRISPR-based rapid DNA repositioning strategy and the early intranuclear life of HSV-1

   Juan Xiang, Chaoyang Fan ... Pei Xu

   An inducible two-component CRISPR-based platform that rapidly repositions HSV-1 genomes to the nuclear edge unveils intranuclear space heterogeneity for the incoming viral genomes and dynamic stages of the host-virus interplay during early infection.
4. 1. Neuroscience

   Rodent ultrasonic vocal interaction resolved with millimeter precision using hybrid beamforming

   Max L Sterling, Ruben Teunisse, Bernhard Englitz

   The accuracy of the Hybrid Vocalization Localizer (HyVL) brings a revolution to the study of social vocalizations of rodents and other animals, where vocalizations often occur in close proximity, and will empower downstream analysis of sequence and semantic analyses.
5. 1. Developmental Biology

   Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch in C. elegans

   Taylor N. Medwig-Kinney, Brian A. Kinney ... David Q. Matus
6. 1. Neuroscience
   2. Structural Biology and Molecular Biophysics

   Molecular tuning of sea anemone stinging

   Lily S He, Yujia Qi ... Nicholas W Bellono
7. 1. Cell Biology
   2. Neuroscience

   Translational regulation enhances distinction of cell types in the nervous system

   Toshiharu Ichinose, Shu Kondo ... Hiromu Tanimoto
8. 1. Neuroscience

   Different rules for binocular combination of luminance flicker in cortical and subcortical pathways

   Federico G Segala, Aurelio Bruno ... Daniel H Baker

   Binocular combination of luminance signals exhibits strong interocular suppression in pathways governing the pupil response, and weak interocular suppression in cortical pathways subserving perception.
9. 1. Genetics and Genomics

   The DBL-1/TGF-β signaling pathway tailors behavioral and molecular host responses to a variety of bacteria in Caenorhabditis elegans

   Bhoomi Madhu, Mohammed Farhan Lakdawala, Tina L Gumienny
10. 1. Neuroscience

    Optogenetic induction of appetitive and aversive taste memories in Drosophila

    Meghan Jelen, Pierre-Yves Musso ... Michael D Gordon