Highlights

  • Vocal motifs in orangutans

    Evidence for ‘recursive’ vocal structures in wild animals has implications for the evolution of language. (Photo: Madeleine E Hardus CC-BY)

    Adriano R Lameira, Madeleine E Hardus ... Marco Gamba
    Research Article
  • Secretion secrets

    Experiments reveals how post-invasion protein secretion in the parasite Toxoplasma gondii differs from the pre-invasion process.

    Sara Chelaghma, Huiling Ke ... Ross F Waller
    Research Article Updated
  • DKK3 and Alzheimer’s disease

    Downregulation of DKK3, a protein that is elevated in Alzheimer’s disease, restores synapse integrity and memory in a mouse model of the disease.

    Nuria Martin Flores, Marina Podpolny ... Patricia C Salinas
    Research Article

Latest research

    1. Genetics and Genomics
    2. Evolutionary Biology

    Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

    Florian Bénitière, Anamaria Necsulea, Laurent Duret
    1. Immunology and Inflammation

    Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

    Preksha Gaur, Yesheswini Rajendran ... Chittur V Srikanth
    1. Cancer Biology

    Large pan-cancer cell screen coupled to (phospho-)proteomics underscores high-dose vitamin C as a potent anti-cancer agent

    Andrea Vallés-Martí, Franziska Böttger ... Connie R Jiménez
    1. Evolutionary Biology

    Trophic diversity and evolution in Enantiornithes: a synthesis including new insights from Bohaiornithidae

    Case Vincent Miller, Jen A. Bright ... Michael Pittman
    1. Developmental Biology
    2. Neuroscience

    RNA fusion in human retinal development

    Wen Wang, Xiao Zhang ... Zi-Bing Jin
    Chimeric RNAs are widely distributed spatiotemporally during human retinal development and have important regulatory functions, such as silencing of CTNNBIP1-CLSTN1 biasing the progenitor cells toward the RPE cell fate at the expense of neural retinal cell fates.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation

    Carolline Ascenção, Jennie R Sims ... Marcus B Smolka
    A Topbp1 mutant mouse reveals a non-canonical role for the ATR-TOPBP1 signaling axis in meiosis, separating ATR signaling and meiotic sex chromosome inactivation from sex body formation.