Highlights

Latest research

    1. Neuroscience

    Locus coeruleus modulation of single-cell representation and population dynamics in the mouse prefrontal cortex during attentional switching

    Marco Nigro, Lucas Silva Tortorelli ... Hongdian Yang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination

    Nikesh M Kumar, Taylor L Cooper ... Patrick T McGrath
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice

    Sarah G Donofrio, Cheryl Brandenburg ... Roy V Sillitoe
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease

    Chemostat culturing reduces fecal eukaryotic virus load and delays diarrhea after virome transplantation

    Simone Margaard Offersen, Signe Adamberg ... Anders Brunse
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Virtual Brain Inference (VBI): A flexible and integrative toolkit for efficient probabilistic inference on virtual brain models

    Abolfazl Ziaeemehr, Marmaduke Woodman ... Meysam Hashemi
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

    Arnaud N’Guessan, Wen Yuan Tong ... Alex N Nguyen Ba
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Convincing
    1. Medicine

    Gamma Knife Stereotactic radiotherapy combined with tislelizumab as later-line therapy in hpMMR/MSS/MSI-L metastatic colorectal cancer: A Phase II Trial Analysis

    Yiran Zhang, Hanyang Guan ... Jinghua Pan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Modeling hereditary diffuse leukoencephalopathy with axonal spheroids using microglia-sufficient brain organoids

    Wei Jie Wong, Yi Wen Zhu ... Florent Ginhoux
    Co-culture between donor-derived iPSC-induced macrophages and forebrain organoids revealed microglial impairment leading to the degenerative neuro-environment in HDLS.