Latest research

1. 1. Computational and Systems Biology
   2. Neuroscience

   Visuomotor learning from postdictive motor error

   Jana Masselink, Markus Lappe

   Visual, motor, and forward model gains learn from a postdictive update of space to keep perception and saccadic motor function aligned.
2. 1. Neuroscience

   Egr2 induction in spiny projection neurons of the ventrolateral striatum contributes to cocaine place preference in mice

   Diptendu Mukherjee et al.

   The ventrolateral striatum is found to be recruited during the encoding of cocaine preference, within which Egr2-expressing ensembles are functionally important, as is the expression of Egr2 within them.
3. 1. Microbiology and Infectious Disease

   Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers

   Qing Yang et al.

   A quick and portable test makes saliva samples turn yellow when people are carrying SARS-CoV-2, the virus that causes COVID-19.
4. 1. Evolutionary Biology
   2. Physics of Living Systems

   Global epistasis emerges from a generic model of a complex trait

   Gautam Reddy, Michael M Desai

   Predictable patterns of fitness evolution observed in microbial evolution experiments can emerge generically as a consequence of widespread epistatic interactions between mutations.
5. 1. Neuroscience

   Analysis of ultrasonic vocalizations from mice using computer vision and machine learning

   Antonio HO Fonseca et al.

   An open-source tool based on computational vision and machine learning shows high accuracy and sensitivity in the analysis of ultrasonic vocalizations.
6. 1. Cell Biology

   Glucose restriction drives spatial reorganization of mevalonate metabolism

   Sean Rogers et al.

   Genetic and biochemical analyses, coupled with fluorescence imaging, reveal that spatial compartmentalization of HMG-CoA Reductases at yeast ER-lysosome contacts modulates mevalonate pathway flux during glucose restriction, enabling metabolic adaptation.
7. 1. Neuroscience

   Network dynamics underlying OFF responses in the auditory cortex

   Giulio Bondanelli et al.

   Computational modeling demonstrates that population dynamics of neural calcium activity following stimulus offset are consistent with a network mechanism based on recurrent interactions.
8. 1. Computational and Systems Biology
   2. Stem Cells and Regenerative Medicine

   The biphasic and age-dependent impact of Klotho on hallmarks of aging and skeletal muscle function

   Zachary Clemens et al.
9. 1. Immunology and Inflammation
   2. Medicine

   Bacterial-fungal interactions in the neonatal gut influence asthma outcomes later in life

   Rozlyn CT Boutin et al.
10. 1. Computational and Systems Biology

    A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice.

    Michael A Petr et al.