Highlights

  • Replication in Drosophila studies

    An analysis of 400 articles on the immune response in Drosophila highlights a need for caution regarding the replicability of certain claims.

    Hannah Westlake, Fabrice David ... Bruno Lemaitre
    Reviewed Preprint Updated
  • Tsetse fly feeding adaptations

    Investigations into the biomechanics of tsetse fly blood feeding reveal that subtle anatomical adaptations enable the penetration of a diverse range of host hides.

    Stephan Löwe, Laura Hauf ... Markus Engstler
    Research Article
  • Anatomy of taste and texture

    Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures.

    Vincent Richter, Tilman Triphan ... Andreas S Thum
    Research Article
  • Neurosecretory connections

    Connectomic and transcriptomic analyses reveal the anatomical and functional organisation of neurosecretion in the Drosophila brain.

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Research Article
  • AI in research communication

    eLife has partnered on a number of projects harnessing AI for improving human and machine reader engagement with research.

    Inside eLife
  • Explore our new collection

    Delve into leading research on Lifestyle, Environment and Epigenetic Inheritance.

    Collection

Latest research

    1. Neuroscience

    Simple methods to acutely measure multiple timing metrics among the sexual repertoire of male Drosophila

    Yutong Song, Hongyu Miao ... Woo Jae Kim
    DrosoMating is a streamlined software and open-hardware platform that automates high-throughput temporal profiling of male Drosophila courtship and mating behaviors with high accuracy.
    1. Neuroscience

    Expectation-driven gain modulation of preparatory spatial attention

    Dirk van Moorselaar, Stefan van der Stigchel
    Expectations about visual search difficulty enhance processing at attended locations by strengthening attentional signals rather than narrowing the spatial focus of attention.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kinesin-1 holoenzyme assembly coordinates cargo-adaptor recognition with heavy-chain autoinhibition

    Jingling Niu, Mengmeng Zhang ... Chao Wang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Global Nernstian astrocytic depolarization breaks down during local synaptic input

    Ryo J Nakatani, Erik De Schutter
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Congruent neuronal modulation across competing actions challenges the role of the substantia nigra in action selection

    Lingfeng Hou, Derin Timuçin ... John Assad
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Solid
    1. Cell Biology
    2. Neuroscience

    Neuropeptides NLP-10 and FLP-18 stimulate lipid catabolism in chronically diet-restricted Caenorhabditis elegans

    Jiaming Liu, Liyun Lin ... Jintao Luo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    Mouse models with human antibody repertoires for inducing multiple lineages of HIV-1 broadly neutralizing antibodies

    Ming Tian, Hwei-Ling Cheng ... Frederick W Alt
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Hippocampal representations differentiate reactive and anticipatory responses during foraging under threat

    Chelsey C Damphousse, Olivia L Calvin, A David Redish
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Developmental Landscape of Gradients in Human Hippocampus

    Debin Zeng, Qiongling Li ... Shuyu Li
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid