Highlights

  • Complex connections

    Optogenetics reveals that interactions between the basal ganglia and the pedunculopontine nucleus (PPN), a region that has a central role in motor control, are more complex than previously thought.

    Michel Fallah, Kenea C Udobi ... Rebekah C Evans
    Research Article
  • Early influences on cell fate

    Cells that polarize early during the 8-cell stage of development in mouse embryos are more likely to become part of the placenta.

    Adiyant Lamba, Meng Zhu ... Magdalena Zernicka-Goetz
    Reviewed Preprint Updated
  • Aggression in female gorillas

    Female-on-female aggression in gorillas depends on the relative numbers of males and females in the group, and on the reproductive state of the gorilla being aggressive.

    Nikolaos Smit, Martha M Robbins
    Research Article

Latest research

    1. Neuroscience

    Decision-making components and times revealed by the single-trial electro-encephalogram

    Gabriel Weindel, Jelmer P Borst, Leendert van Maanen
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Disinformation elicits learning biases

    Juan Vidal-Perez, Raymond J Dolan, Rani Moran
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics
    2. Physics of Living Systems

    Detecting directed motion and confinement in single-particle trajectories using hidden variables

    François Simon, Guillaume Ramadier ... Lucien E Weiss
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Developmental Biology

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Exceptional
    • Solid
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Short heat shock factor A2 confers heat sensitivity in Arabidopsis: Insights into heat resistance and growth balance

    Wanxia Chen, Jiaqi Zhao ... Xiaoting Qi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease

    Mei-Lun Huang, Yusuke Suzuki ... Itaru Imayoshi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Structural and functional evidence supports re-defining mouse higher order visual areas into a single area V2

    Declan P Rowley, Madineh Sedigh-Sarvestani
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Evolutionary Biology
    2. Immunology and Inflammation

    Newly discovered and conserved role of IgM against viral infection in an early vertebrate

    Weiguang Kong, Xinyou Wang ... Zhen Xu
    sIgM plays a role in viral neutralization across both primitive and modern vertebrates by following conserved principles in the development of specialized antiviral immunity.
    1. Evolutionary Biology

    Meaning-making behavior in a small-brained hominin, Homo naledi, from the late Pleistocene: contexts and evolutionary implications

    Agustín Fuentes, Marc Kissel ... Lee R Berger
    Evidence for H. naledi and increasing recognition of meaning-making behavior across the later Pleistocene suggests that the hominin emotional, socio-cognitive niche is broader and more significant than previously thought.
    1. Immunology and Inflammation

    Hematopoietic stem and progenitor cells as a reservoir for trained immunity

    Brandon T Tran, Vidthiya Jeyanathan ... Katherine Y King
    Inflammation supports selection, differentiation bias, and epigenetic reprogramming of hematopoietic stem and progenitor cells to generate innate immune memory.