Highlights

  • Ribbon formation in hair cells

    Live imaging reveals role of microtubule networks in formation of ribbon synapses in zebrafish hair cells.

    Saman Hussain, Katherine Pinter ... Katie S Kindt
    Reviewed Preprint Updated
  • Genetics and structural color

    Structural color in a Flavobacterium can be changed by a mutation to a gene that is involved in polysaccharide metabolism.

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Reviewed Preprint Updated
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Cell Biology
    2. Neuroscience

    Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

    Xue Chen, Deng Pan ... Yanrui Yang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Genetic compensation in podocalyxin-like mutants during zebrafish liver development

    Alexis N Ross, Natalie M Miscik ... Kimberley Jane Evason
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Sequence action representations contextualize during early skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Insights from aquaporin structures into drug-resistant sleeping sickness

    Modestas Matusevicius, Robin A Corey ... Simone N Weyand
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation

    Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin

    Eric S Weiss, Toshiro Hirai ... Daniel H Kaplan
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading

    Francesco Marocco, Sabrina Garbo ... Marco Tripodi
    PCBP2 promotes miRNA cell retention by counteracting SYNCRIP-dependent miRNAs EV loading.
    1. Structural Biology and Molecular Biophysics

    Structural insights into heterohexameric assembly of epilepsy-related ligand–receptor complex LGI1–ADAM22

    Takayuki Yamaguchi, Kei Okatsu ... Shuya Fukai
    Cryo-electron microscopy and high-speed atomic force microscopy analyses of an epilepsy-related ligand–receptor complex LGI1–ADAM22 reveal the three-dimensional structure and dynamics of the 3:3 heterohexameric assembly of LGI1–ADAM22.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control in HeLa cells

    Mykola Roiuk, Marilena Neff, Aurelio A Teleman
    Although eIF2A is thought to be a translation initiation factor, loss of eIF2A has no effect on cellular mRNA translation in either unstressed or stressed conditions.
    1. Neuroscience

    Hunger shifts attention and attribute weighting in dietary choice

    Jennifer March, Sebastian Gluth
    Extended multi-attribute attentional drift diffusion model reveals how attentional dynamics and weight shifts lead to less healthy decisions under hunger.
    1. Neuroscience

    Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits

    Yaroslav Molkov, Anke Borgmann ... Jeffrey Smith
    A robust method to infer excitatory and inhibitory synaptic conductances from neuronal recordings reveals functional circuit organization in rhythmic networks.