Highlights

  • Secrets of metamorphosis

    Interactions between different G-protein signalling pathways ensure that metamorphosis begins in a timely manner in the chordate Ciona.

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Research Article
  • Genetics and structural color

    Structural color in a Flavobacterium can be changed by a mutation to a gene that is involved in polysaccharide metabolism.

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Reviewed Preprint Updated
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Neuroscience

    The Self-Interest of Adolescents Overrules Cooperation in Social Dilemmas

    Xiaoyan Wu, Hongyu Fu ... Chao Liu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Neuroscience

    Synchronous Ensembles of Hippocampal CA1 Pyramidal Neurons During Novel Exploration

    En-Li Chen, Tsai-Wen Chen ... Bei-Jung Lin
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Incomplete
    1. Cell Biology

    The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the Drosophila gut

    Yueliang Zhang, Sara B Noya ... Amita Sehgal
    The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.
    1. Neuroscience

    Acquisition of auditory discrimination mediated by different processes through two distinct circuits linked to the lateral striatum

    Susumu Setogawa, Takashi Okauchi ... Kazuto Kobayashi
    Two lateral striatal subregions integrate the acquisition of stimulus-based decision-making in spatiotemporally and functionally different manners, challenging the prior model through a dominance change from the associative to sensorimotor subregions.
    1. Neuroscience

    Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking

    Claire Cooper, Daniel Parthier ... Dietmar Schmitz
    The fine-tuning of mutual inhibition and disinhibition of sleep-regulating neurons and also the memory consolidation that occurs during NREM sleep are controlled by oscillations in serotonin levels.
    1. Neuroscience

    Characterization of Postsynaptic Glutamate Transporter Functionality in the Zebrafish Retinal First Synapse Across Different Wavelengths

    Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis

    Yue Wang, Richard Anney, Narun Pat
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mechanism of SK2 channel gating and its modulation by the bee toxin apamin and small molecules

    Samantha J Cassell, Weiyan Li ... Jonathan R Whicher
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    NR2F2 is required in the embryonic testis for fetal Leydig cell development

    Aitana Perea-Gomez, Natividad Bellido Carreras ... Marie-Christine Chaboissier
    NR2F2 regulates fetal Leydig cell differentiation and steroidogenesis in mouse testes, providing mechanistic insight into testis development and the etiology of 46,XY differences in sex development.