Latest research

1. 1. Neuroscience

   A human subcortical network underlying social avoidance revealed by risky economic choices

   Johannes Schultz et al.

   The subjective value of engaging in human social situations, and amygdala and nucleus accumbens activation and their connectivity during social decision-making, vary with social anxiety traits.
2. 1. Immunology and Inflammation

   Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells

   Eugene Park et al.

   Toxoplasma gondii infection leads to conversion of natural killer cells into cells resembling innate lymphoid cells, group 1, that circulate widely, disrupting current notions suggesting that these cells have distinct lineages.
3. 1. Neuroscience

   Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy

   Ying Sun et al.

   Deep brain calcium imaging reveals the abnormal neuronal activity patterns of the amygdala GABAergic neurons in an animal model of human sleep disorder narcolepsy.
4. 1. Neuroscience

   Metacontrol of decision-making strategies in human aging

   Florian Bolenz et al.

   Older adults show reduced adaptation of decision-making strategies to dynamically changing situational demands.
5. 1. Neuroscience

   Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1

   Leanne M Holt et al.
6. 1. Cell Biology

   Golgi localized β1-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCε to regulate cardiac hypertrophy

   Craig A Nash et al.
7. 1. Computational and Systems Biology
   2. Neuroscience

   Statistical context dictates the relationship between feedback-related EEG signals and learning

   Matthew R Nassar et al.
8. 1. Biochemistry and Chemical Biology
   2. Microbiology and Infectious Disease

   Subtle selectivity in a pheromone sensor triumvirate desynchronizes competence and predation in a human gut commensal

   Johann Mignolet et al.

   A new cell–cell communication system in Streptococcus salivarius, a human gut commensal, discriminates between close signaling molecules to specifically produce bacteriocin-based antimicrobials and disconnects it from foreign DNA acquisition.
9. 1. Immunology and Inflammation

   B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

   Lieselotte SM Kreuk et al.

   Microbial-sensing TLRs drive responses to the microbiota, while nucleic-acid sensing TLRs control responses to endogenous ligands, revealing novel regulation of B-1a responses through integrated BCR/TLR mediated activation.
10. 1. Immunology and Inflammation

    TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections

    Hannah P Savage et al.

    B-1 cell unresponsiveness to antigen-stimulation is overcome during infections when Toll-like receptor engagement removes negative regulators of B cell receptor signaling, thereby supporting B-1 cell differentiation to IgM-secreting plasmablasts.