All research categories

Highlights

  • Deep mutational scanning

    High-resolution approach has been used to assess the effect of more than 6000 protein-coding variants in a G protein-coupled receptor associated with obesity.

    Conor J Howard, Nathan S Abell ... Nathan B Lubock
    Reviewed Preprint Updated

  • Cell mechanics and metastasis

    The discovery of a pro-invasive mechanotransduction pathway driven by cell crowding suggests that an ion channel called TRPV4 may be a promising therapeutic target for inhibiting metastasis.

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Reviewed Preprint Updated

  • Social behaviors in mice

    A cell atlas for the preoptic area of the brain could be used to investigate how neuronal traits may be evolving to give rise to innate differences in social behavior across species.

    Jenny Chen, Phoebe R Richardson ... Hopi E Hoekstra
    Reviewed Preprint Updated

Latest research

    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing

    Jiale Zhou, Ding Zhao ... Zhanjun Li
    Revised
    Reviewed Preprint v4
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Enabling brain-wide mapping of layer-specific functional connectivity at 3T via layer-dependent fMRI with draining-vein suppression

    Wei-Tang Chang, Weili Lin, Kelly S Giovanello
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Exceptional
    1. Neuroscience

    Effects of nicotine compared to placebo gum on sensitivity to pain and mediating effects of peak alpha frequency

    Samantha K Millard, Alan KI Chiang ... David A Seminowicz
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Decoding the hidden variabilities in mPFC descending pathways across emotional states

    Chien-Hsien Lai, Gyeongah Park ... Jianyang Du
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Cancer Biology

    Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

    Weijie Wu, Miao Yu ... Hongquan Zhang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

    Xiaoyu Meng, Yezhang Zhu ... Lie Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

    Darshika Bohra, Zubairul Islam ... Dimple Notani
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Computational and Systems Biology

    A mathematical model that predicts human biological age from physiological traits identifies environmental and genetic factors that influence aging

    Sergiy Libert, Alex Chekholko, Cynthia Kenyon
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    The ALS-associated co-chaperone DNAJC7 mediates neuroprotection against proteotoxic stress by modulating HSF1 activity

    Andrew C Fleming, Nalini R Rao ... Evangelos Kiskinis
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
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Magazine

    1. Cell Biology
    2. Developmental Biology

    Ovarian Biology: Revisiting the rete ovarii

    Yan Zhang, Hua Zhang
    1. Microbiology and Infectious Disease

    Viruses: How herpes is assembled

    Dawid S Zyla
    1. Neuroscience

    Metabolism: Insulin control in fruit flies

    Omowumi Kayode
  4. Anne Urai and Clare Kelly (CC BY 4.0)

    Activism and Science: Anne Urai and Clare Kelly on responding to the climate and biodiversity crises

    1. Developmental Biology
    2. Genetics and Genomics

    Vascular Development: Enhancing our understanding of endothelial cells

    Guillermo Luxán
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Cellular Energy Production: Mycofactocin and the mycobacterial electron transport chain

    Stephanie M Stuteley, Ghader Bashiri
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Transcription: The plusses and minuses of DNA torsion

    Steven Henikoff, David L Levens
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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