All research categories

Highlights

  • Evolutionary interplay

    The evolutionary history of a family of beetles called Belidae has been influenced by the breakup of the supercontinent Gondwana and the rise of angiosperms.

    Xuankun Li, Adriana E Marvaldi ... Duane D McKenna
    Research Article

  • Targeting a methyltransferase

    The SARS-CoV-2 main protease targets an enzyme called TRMT1 that modifies transfer RNA.

    Angel D'Oliviera, Xuhang Dai ... Jeffrey S Mugridge
    Research Article

  • eLife’s new Editor-in-Chief

    Timothy Behrens has been appointed Editor-in-Chief to lead our efforts to improve research communication for all.

    Press Pack

Latest research

    1. Computational and Systems Biology
    2. Genetics and Genomics

    Risk factors affecting polygenic score performance across diverse cohorts

    Daniel Hui, Scott Dudek ... Marylyn D Ritchie
    Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Neuroscience

    Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

    Hyun Jee Lee, Jingting Liang ... Hang Lu
    Highly accurate automated cell annotation in multi-cell imaging enables cell identification and reduces subjectivity in Caenorhabditis elegans neural image processing.
    1. Physics of Living Systems

    Effects of growth feedback on adaptive gene circuits: A dynamical understanding

    Ling-Wei Kong, Wenjia Shi ... Ying-Cheng Lai
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

    Rebecca G Jaszczak, Jay W Zussman ... Diana J Laird
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Evolutionary Biology

    Inversions Can Accumulate Balanced Sexual Antagonism: Evidence from Simulations and Drosophila Experiments

    Christopher S McAllester, John E Pool
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology

    Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

    Gabriella O Estevam, Edmond M Linossi ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Ecology

    A circadian clock drives behavioral activity in Antarctic krill (Euphausia superba) and provides a potential mechanism for seasonal timing

    Lukas Hüppe, Dominik Bahlburg ... Bettina Meyer
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Plant Biology
    2. Ecology

    Strip cropping designed for maintaining productivity increases ground beetle biodiversity

    Luuk Croijmans, Fogelina Cuperus ... Erik H Poelman
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
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Magazine

    1. Genetics and Genomics

    Down Syndrome: How a gene fuels ear infections

    Sedigheh Delmaghani, Aziz El-Amraoui
    1. Chromosomes and Gene Expression

    Cryogenic Electron Microscopy: MagIC beads for scarce macromolecules

    Carlos Moreno-Yruela, Beat Fierz
    1. Cell Biology

    Aging: Restoring bone healing potential

    Inês Sequeira
    1. Developmental Biology

    Brain Development: Single cells tell it all

    Margaret Hines, Elias Oxman ... Irene Zohn
  5. An isopod, well-adapted to the harsh conditions of arid-lands, crawls on the desert floor in search of leaf litter

    Episode 96: December 2024

    1. Computational and Systems Biology

    Cellular Respiration: Mapping mitochondrial aging

    Alessandro Bitto
    1. Ecology

    Disease Transmission: Interactions between wild pigs and the spread of disease

    Mercury Shitindo
  8. See more Magazine articles

Research categories

  1. Biochemistry and Chemical Biology
  2. Cancer Biology
  3. Cell Biology
  4. Chromosomes and Gene Expression
  5. Computational and Systems Biology
  6. Developmental Biology
  7. Ecology
  8. Epidemiology and Global Health
  9. Evolutionary Biology
  10. Genetics and Genomics
  11. Immunology and Inflammation
  12. Medicine
  13. Microbiology and Infectious Disease
  14. Neuroscience
  15. Physics of Living Systems
  16. Plant Biology
  17. Stem Cells and Regenerative Medicine
  18. Structural Biology and Molecular Biophysics
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