Highlights

  • Secrets of metamorphosis

    Interactions between different G-protein signalling pathways ensure that metamorphosis begins in a timely manner in the chordate Ciona.

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Research Article
  • Genetics and structural color

    Structural color in a Flavobacterium can be changed by a mutation to a gene that is involved in polysaccharide metabolism.

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Reviewed Preprint Updated
  • Exploring VNC neurons

    A library of genetic driver lines makes it possible to manipulate specific neuronal hemilineages in flies.

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Research Article

Latest research

    1. Neuroscience

    The relationship between cognitive abilities and mental health as represented by cognitive abilities at the neural and genetic levels of analysis

    Yue Wang, Richard Anney, Narun Pat
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Mechanism of SK2 channel gating and its modulation by the bee toxin apamin and small molecules

    Samantha J Cassell, Weiyan Li ... Jonathan R Whicher
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Characterization of Postsynaptic Glutamate Transporter Functionality in the Zebrafish Retinal First Synapse Across Different Wavelengths

    Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Developmental Biology

    NR2F2 is required in the embryonic testis for fetal Leydig cell development

    Aitana Perea-Gomez, Natividad Bellido Carreras ... Marie-Christine Chaboissier
    NR2F2 regulates fetal Leydig cell differentiation and steroidogenesis in mouse testes, providing mechanistic insight into testis development and the etiology of 46,XY differences in sex development.
    1. Microbiology and Infectious Disease

    Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus

    My Tran, Angel J Hernandez Viera ... Charlie Y Mo
    In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.
    1. Neuroscience

    The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target

    Lisa M Kroell, Martin Rolfs
    Foveal sensitivity to the features of an imminent saccade target increases with the target’s conspicuity, supporting foveal prediction as a viable mechanism for maintaining visual continuity in high-contrast, naturalistic environments.
    1. Neuroscience

    Longitudinal tracking of neuronal activity from the same cells in the developing brain using Track2p

    Jure Majnik, Manon Mantez ... Rosa Cossart
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Developmental Biology

    Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

    Shuo Chen, Jinxiu Liang ... Peidong Han
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    SETD2 suppresses tumorigenesis in a KRASG12C-driven lung cancer model and its catalytic activity is regulated by histone acetylation

    Ricardo J Mack, Natasha M Flores ... Or Gozani
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging

    Siqi Wang, Danyue Dong ... Zefeng Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid