Highlights

Latest research

    1. Chromosomes and Gene Expression

    Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response

    Jiayi Fan, Nalini Dhingra ... Xiaolan Zhao
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Deletion of the moeA gene in Flavobacterium IR1 drives structural color shift from green to blue and alters polysaccharide metabolism

    Álvaro Escobar Doncel, Constantinos Patinios ... Colin J Ingham
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Evolutionary Biology

    Effective population size does not explain long-term variation in genome size and transposable element content in animals

    Alba Marino, Gautier Debaecker ... Benoit Nabholz
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

    Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    A causal role of the NMDA receptor in recurrent processing during perceptual integration

    Samuel Noorman, Timo Stein ... Simon van Gaal
    Memantine selectively improves neural decoding of attended illusory contours, revealing NMDA receptor-dependent enhancement of feedback processing in human visual perception.
    1. Cancer Biology

    A multi-gene predictive model for the radiation sensitivity of nasopharyngeal carcinoma based on machine learning

    Kailai Li, Junyi Liang ... Hui Meng
    A machine learning-derived multi-gene score effectively predicts radiation sensitivity in nasopharyngeal carcinoma by integrating immune characteristics and radiosensitivity-related pathways.
    1. Developmental Biology

    Stimulatory and inhibitory G-protein signaling relays drive cAMP accumulation for timely metamorphosis in the chordate Ciona

    Akiko Hozumi, Nozomu M Totsuka ... Yasunori Sasakura
    Ascidian larvae use cAMP as the molecular timer to infer the timing initiating metamorphosis.
    1. Immunology and Inflammation

    Trained immunity: A new player in cancer immunotherapy

    Shu Li, Yi Zou ... Jun Yan
    Trained immunity is a form of innate immune cell memory that is being developed as a novel immunotherapeutic approach for cancer treatment.
    1. Developmental Biology
    2. Neuroscience

    In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

    Kawsar Hossain, Madeline Smith ... Stephen W Santoro
    The neurogenesis rates of some olfactory sensory neuron subtypes are selectively accelerated in mice that are exposed to odors that stimulate those subtypes.