Breakthroughs in aging-related research are revealing details of how cellular processes and tissue functions decline during aging and have pinpointed longevity factors conserved among eukaryotes. In parallel, investigations in model organisms are uncovering potential approaches to extend lifespan in humans.
To highlight recent advances in the mechanistic understanding of aging and interventions that extend longevity, eLife is pleased to present a Special Issue devoted to this exciting topic. This issue presents a collection of highly influential research selected for publication by a specially convened group of experts.
To support the launch of the issue, Senior Editors Jessica Tyler and Matt Kaeberlain explore a new era for research into aging in their Editorial.